ID A0A0G1BK96_9BACT Unreviewed; 309 AA.
AC A0A0G1BK96;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 13-SEP-2023, entry version 31.
DE RecName: Full=Transcription antitermination protein NusB {ECO:0000256|HAMAP-Rule:MF_00073};
DE AltName: Full=Antitermination factor NusB {ECO:0000256|HAMAP-Rule:MF_00073};
GN Name=nusB {ECO:0000256|HAMAP-Rule:MF_00073};
GN ORFNames=UU98_C0010G0006 {ECO:0000313|EMBL:KKS37903.1};
OS Parcubacteria group bacterium GW2011_GWD2_42_14.
OC Bacteria.
OX NCBI_TaxID=1618944 {ECO:0000313|EMBL:KKS37903.1, ECO:0000313|Proteomes:UP000033822};
RN [1] {ECO:0000313|EMBL:KKS37903.1, ECO:0000313|Proteomes:UP000033822}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- FUNCTION: Involved in transcription antitermination. Required for
CC transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC {ECO:0000256|HAMAP-Rule:MF_00073}.
CC -!- SIMILARITY: Belongs to the NusB family. {ECO:0000256|ARBA:ARBA00005952,
CC ECO:0000256|HAMAP-Rule:MF_00073}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKS37903.1}.
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DR EMBL; LCCS01000010; KKS37903.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1BK96; -.
DR STRING; 1618944.UU98_C0010G0006; -.
DR PATRIC; fig|1618944.3.peg.403; -.
DR Proteomes; UP000033822; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription termination; IEA:UniProtKB-UniRule.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR CDD; cd00619; Terminator_NusB; 1.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR Gene3D; 1.10.940.10; NusB-like; 1.
DR HAMAP; MF_00073; NusB; 1.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR InterPro; IPR035926; NusB-like_sf.
DR InterPro; IPR011605; NusB_fam.
DR InterPro; IPR006027; NusB_RsmB_TIM44.
DR NCBIfam; TIGR01951; nusB; 1.
DR PANTHER; PTHR11078:SF3; ANTITERMINATION NUSB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11078; N UTILIZATION SUBSTANCE PROTEIN B-RELATED; 1.
DR Pfam; PF00293; NUDIX; 1.
DR Pfam; PF01029; NusB; 1.
DR SUPFAM; SSF55811; Nudix; 1.
DR SUPFAM; SSF48013; NusB-like; 1.
DR PROSITE; PS51462; NUDIX; 1.
PE 3: Inferred from homology;
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00073};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00073};
KW Transcription antitermination {ECO:0000256|ARBA:ARBA00022814,
KW ECO:0000256|HAMAP-Rule:MF_00073};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_00073}.
FT DOMAIN 169..301
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
SQ SEQUENCE 309 AA; 34642 MW; 57D78417458FAE65 CRC64;
MSNRHLSRSI VLQTLFEWDT NNEEGNGKTD APEVILSRNI EEFATDSKDK PFMKRLLDGV
ITKQSDLDAV ISKAAPEWPI DKIARVDRNI LRLGLYELLF SDRKEVPAKV AINEAIELAK
NFGGDSSGGF INGVIGGVYK ELGEPGKDEV STKNKKSRTQ PLVPYELMPI DRKAGAVVYA
EHDGDVYVAL VHDVFGHWTL SKGGVEEGES DEEATVREIK EEMDLDIKIV EKLGENEYVA
SHPEKGKIRK HVSYYLAESP FTEVKLEEGK GGLDDARWFK LADILELNFY HDMLPIITKA
INILLSLKK
//
