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Database: UniProt
Entry: A0A0G1H2D8_9BACT
LinkDB: A0A0G1H2D8_9BACT
Original site: A0A0G1H2D8_9BACT 
ID   A0A0G1H2D8_9BACT        Unreviewed;       462 AA.
AC   A0A0G1H2D8;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   05-JUL-2017, entry version 16.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=UV95_C0001G0269 {ECO:0000313|EMBL:KKT13732.1};
OS   Candidatus Falkowbacteria bacterium GW2011_GWF2_43_32.
OC   Bacteria; Candidatus Falkowbacteria.
OX   NCBI_TaxID=1618643 {ECO:0000313|EMBL:KKT13732.1, ECO:0000313|Proteomes:UP000034431};
RN   [1] {ECO:0000313|EMBL:KKT13732.1, ECO:0000313|Proteomes:UP000034431}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a
RT   large radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KKT13732.1}.
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DR   EMBL; LCGL01000001; KKT13732.1; -; Genomic_DNA.
DR   EnsemblBacteria; KKT13732; KKT13732; UV95_C0001G0269.
DR   PATRIC; fig|1618643.3.peg.319; -.
DR   Proteomes; UP000034431; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000034431};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000034431}.
FT   DOMAIN      156    288       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      366    435       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     164    171       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
FT   COILED      425    452       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   462 AA;  52227 MW;  FA7EDF53DF8B6CA4 CRC64;
     MTNEQIWQAV LGEIEIGLSR ANFVTWFKDT FLSSFENDRV IICVPNAFVK KWLEEKYHKN
     ILGALENVSK KPIQEIIYKI ELRRGGQAPL ATKSETKIET PIQTIKNDSS VSRESNGGSN
     RFGLNPRYVF ENFIVGRGNE LAHAACLAVA ENLGKSYNPL FIYGGVGLGK THLLQAIGGV
     VAKTSDKILY TTSEKFTNNY IQAVKTGKAK EFKNLYRNVD LLLVDDVQFM GGKDGTQEEF
     FHTFNELQQN DKQIVLTSDR PPKSLPAIEK RLISRFESGM VADIGKPDIE TKIAILEKKS
     LEKNFPLDKE ILSYIADHVQ NNIRELEGAL TKVIASHQFK GLSPSLKTVK EILNDYVSNI
     QLRSLTPKEI IETTAKFYNL NYKDLTGESR KKELVWPRQI AIFLIREELG TSYPAIGAEL
     GGRDHTTAMH SYNKISQEIK ELENKKIKQE VDSIRQLFTA AY
//
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