ID A0A0G1N4S3_9BACT Unreviewed; 744 AA.
AC A0A0G1N4S3;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=valine--tRNA ligase {ECO:0000256|ARBA:ARBA00013169};
DE EC=6.1.1.9 {ECO:0000256|ARBA:ARBA00013169};
DE AltName: Full=Valyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00029936};
GN ORFNames=UW89_C0012G0012 {ECO:0000313|EMBL:KKT88072.1};
OS Parcubacteria group bacterium GW2011_GWB1_45_10.
OC Bacteria.
OX NCBI_TaxID=1618877 {ECO:0000313|EMBL:KKT88072.1, ECO:0000313|Proteomes:UP000033817};
RN [1] {ECO:0000313|EMBL:KKT88072.1, ECO:0000313|Proteomes:UP000033817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-
CC tRNA(Val); Xref=Rhea:RHEA:10704, Rhea:RHEA-COMP:9672, Rhea:RHEA-
CC COMP:9708, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57762,
CC ChEBI:CHEBI:78442, ChEBI:CHEBI:78537, ChEBI:CHEBI:456215; EC=6.1.1.9;
CC Evidence={ECO:0000256|ARBA:ARBA00001624};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKT88072.1}.
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DR EMBL; LCKC01000012; KKT88072.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1N4S3; -.
DR STRING; 1618877.UW89_C0012G0012; -.
DR PATRIC; fig|1618877.3.peg.386; -.
DR Proteomes; UP000033817; Unassembled WGS sequence.
DR GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004832; F:valine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006438; P:valyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd07962; Anticodon_Ia_Val; 1.
DR Gene3D; 3.40.50.620; HUPs; 2.
DR InterPro; IPR002300; aa-tRNA-synth_Ia.
DR InterPro; IPR033705; Anticodon_Ia_Val.
DR InterPro; IPR013155; M/V/L/I-tRNA-synth_anticd-bd.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR009080; tRNAsynth_Ia_anticodon-bd.
DR InterPro; IPR009008; Val/Leu/Ile-tRNA-synth_edit.
DR InterPro; IPR002303; Valyl-tRNA_ligase.
DR NCBIfam; TIGR00422; valS; 1.
DR PANTHER; PTHR11946:SF93; VALINE--TRNA LIGASE, CHLOROPLASTIC_MITOCHONDRIAL 2; 1.
DR PANTHER; PTHR11946; VALYL-TRNA SYNTHETASES; 1.
DR Pfam; PF08264; Anticodon_1; 1.
DR Pfam; PF00133; tRNA-synt_1; 1.
DR PRINTS; PR00986; TRNASYNTHVAL.
DR SUPFAM; SSF47323; Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR SUPFAM; SSF50677; ValRS/IleRS/LeuRS editing domain; 1.
PE 4: Predicted;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:KKT88072.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT DOMAIN 17..592
FT /note="Aminoacyl-tRNA synthetase class Ia"
FT /evidence="ECO:0000259|Pfam:PF00133"
FT DOMAIN 642..743
FT /note="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase
FT anticodon-binding"
FT /evidence="ECO:0000259|Pfam:PF08264"
SQ SEQUENCE 744 AA; 85687 MW; 812295CF70906271 CRC64;
MAGELEKNFE PKGVEEKIYS LWEKENVFTP KIDKKKKPFT IILPLPNAND PMHMGHGMFV
IEDILTRYHI MKGDPTLWLP GADHAGIETQ FVFEKKLAKE GKSRFDFDRE TLFEKLKEFV
EENRLTNKDQ LKRLGFALDW SRYHYSMEPE IVERVLETFM KLHKDGLIYR GERVVHYCTK
CGTSFSDLEV LYEEREDKLY YLDYGPIIIA TTRPETIFAD VAVAINPKHK KIKELKGAEA
IIPLINKKIP VIQDELVDLE FGTGALKITP GHDAVDFEIG SKHRLKTISV VDRSGKMVNV
PEKYLGLKVL KAREETIKDL KAAGKLVKEE PLKHSVGTCY RCGTVIEPMV FPQWFVKTKP
LAEPAIKAVK NGETKIFPQK RFEKMYFDWM ENIKDWNISR QIVWGPRIPA WYCLDCNDSI
RINFLNKKKE VVSGPYKEIK QSYSFEEIKS GLQSLFSTGD ATYQLKDGSC QKCGGPNVIQ
ETDTFDTWFL SGQWPVNTLK ANPGDLEYFY PTSVLDTLWD ILFFWAGRMM MVGLYLTGKV
PFRVIHLHAR VVDKFGKKMS KSKGNVIDPL VMVNQYGADA LRLALVLGVG PASDVSLSDE
KVRGMRNFTN KLWNIGRFII MSSKEQGFQR FEPGMPGLEE VDRAIIESLN KLVKQTTKML
DNYRFGQASE ELFQFIWHEF ADVYIEQSKQ RIKSGDKTVL AVLFHVYSVC LKLLHPFMPF
ITEAVWQKMF AKNNSLLIKE SWPS
//
