ID   A0A0G1RWF7_9BACT        Unreviewed;       479 AA.
AC   A0A0G1RWF7;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:KKU61477.1};
GN   ORFNames=UX85_C0003G0136 {ECO:0000313|EMBL:KKU61477.1};
OS   Candidatus Beckwithbacteria bacterium GW2011_GWB1_47_15.
OC   Bacteria; Candidatus Beckwithbacteria.
OX   NCBI_TaxID=1618371 {ECO:0000313|EMBL:KKU61477.1, ECO:0000313|Proteomes:UP000033860};
RN   [1] {ECO:0000313|EMBL:KKU61477.1, ECO:0000313|Proteomes:UP000033860}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT   radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKU61477.1}.
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DR   EMBL; LCNT01000003; KKU61477.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0G1RWF7; -.
DR   Proteomes; UP000033860; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          71..131
FT                   /note="Penicillin-binding protein dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF03717"
FT   DOMAIN          164..473
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   479 AA;  52160 MW;  53FB74FD09C01137 CRC64;
     MASLVFKWFE AALVAVFMVL VGRVMVLTVW EGSYYRELAE GNRVEVVDLP ADRGVMYDRN
     GVQLVRNTPE GREYIFGKAL AHVLGHVGEI SQFEGDTVGK VGLEKEYDAV LSGQDGALLV
     EKDAEGKLVR EVGRKDPVAG ESLELTVDVS LQQKAFQVLA GRLGAVIASD SQTGEILALV
     SGPAFDPNKV EEALADSKLP LFDRATSGEY PPGSVFKVVT ATAGLEEGRV NESTQIEDTG
     EIVIGDFRYG NWYYDQYGRK EGLLNIVRAI ARSNDIFFYK MGEALGITAL SDWAKYFGVG
     RAVGIDLPGE ANGLMPDPDW KQKYIGESWY LGDTYISAIG QGNILMTPLQ VNQMMSIVAS
     GGRWCRPHLV KSETNCQKLD ISNKTIATVT EGLKQVTETG GTAWPFFDFT VDGERILVAG
     KTGTAEYGDP DDKTHAWFTA FAPADEPEIV VTVLLEGAGE GSNEAAPVAK ELLAEWFRR
//