ID A0A0G1TK64_9BACT Unreviewed; 336 AA.
AC A0A0G1TK64;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Fructose-1,6-bisphosphate aldolase/phosphatase {ECO:0000256|ARBA:ARBA00018635};
DE EC=3.1.3.11 {ECO:0000256|ARBA:ARBA00013093};
GN ORFNames=UY10_C0040G0006 {ECO:0000313|EMBL:KKU82201.1};
OS Microgenomates group bacterium GW2011_GWA2_47_8.
OC Bacteria.
OX NCBI_TaxID=1618503 {ECO:0000313|EMBL:KKU82201.1, ECO:0000313|Proteomes:UP000034016};
RN [1] {ECO:0000313|EMBL:KKU82201.1, ECO:0000313|Proteomes:UP000034016}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-
CC phosphate + phosphate; Xref=Rhea:RHEA:11064, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:32966, ChEBI:CHEBI:43474, ChEBI:CHEBI:57634; EC=3.1.3.11;
CC Evidence={ECO:0000256|ARBA:ARBA00001273};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC {ECO:0000256|ARBA:ARBA00004742}.
CC -!- SUBUNIT: Homooctamer; dimer of tetramers.
CC {ECO:0000256|ARBA:ARBA00011820}.
CC -!- SIMILARITY: Belongs to the FBP aldolase/phosphatase family.
CC {ECO:0000256|ARBA:ARBA00010693}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKU82201.1}.
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DR EMBL; LCOS01000040; KKU82201.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1TK64; -.
DR PATRIC; fig|1618503.3.peg.659; -.
DR UniPathway; UPA00138; -.
DR Proteomes; UP000034016; Unassembled WGS sequence.
DR GO; GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR InterPro; IPR002803; FBPase_V.
DR InterPro; IPR036076; FBPase_V_sf.
DR PANTHER; PTHR38341; FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE/PHOSPHATASE; 1.
DR PANTHER; PTHR38341:SF1; FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE_PHOSPHATASE; 1.
DR Pfam; PF01950; FBPase_3; 1.
DR SUPFAM; SSF111249; Sulfolobus fructose-1,6-bisphosphatase-like; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Gluconeogenesis {ECO:0000256|ARBA:ARBA00022432};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Schiff base {ECO:0000256|ARBA:ARBA00023270}.
SQ SEQUENCE 336 AA; 36628 MW; 566FD7C56E2BE27C CRC64;
MKTAVKSGLL TDARVTFTGD DIALLMIHAK GTDNPDIHKL AWDTFVATTA IAKSQGLYGA
GQDLLKDAFS GNVRGMGPGS AEIEVEERPA EPFLVFAADK CGPGVFNYPL FEAFANPYHN
AGLLLAPEMR EGFTFTIMDV NNVEADRVIT LKVPSDYYDI CTLLRDPNHY VIESVTENAT
GLQAAASSTS RLHNIAGKYV GKDDPVAIVR SQKTFPSTGE ILSPWALAHY TLGDNRGSHH
VAVMPVKQNS IISFFDGPTI VSAAGYCVHE GKLTEAVDLF DQPFWDTIRT KAAEKTLAMR
AQGFYGPAMA GMDELEYTGV VENLKRLNEK FVVRKK
//
