ID A0A0G1U2P2_9BACT Unreviewed; 689 AA.
AC A0A0G1U2P2;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=UvrABC system protein B {ECO:0000256|ARBA:ARBA00029504, ECO:0000256|RuleBase:RU003587};
GN ORFNames=UY18_C0016G0001 {ECO:0000313|EMBL:KKU88321.1};
OS Microgenomates group bacterium GW2011_GWF2_47_9.
OC Bacteria.
OX NCBI_TaxID=1618541 {ECO:0000313|EMBL:KKU88321.1, ECO:0000313|Proteomes:UP000034647};
RN [1] {ECO:0000313|EMBL:KKU88321.1, ECO:0000313|Proteomes:UP000034647}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- SUBUNIT: Forms a heterotetramer with UvrA during the search for
CC lesions. Interacts with UvrC in an incision complex.
CC {ECO:0000256|ARBA:ARBA00026033, ECO:0000256|RuleBase:RU003587}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU003587}.
CC -!- SIMILARITY: Belongs to the UvrB family. {ECO:0000256|ARBA:ARBA00008533,
CC ECO:0000256|RuleBase:RU003587}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKU88321.1}.
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DR EMBL; LCPA01000016; KKU88321.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1U2P2; -.
DR STRING; 1618541.UY18_C0016G0001; -.
DR PATRIC; fig|1618541.3.peg.443; -.
DR Proteomes; UP000034647; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR CDD; cd17916; DEXHc_UvrB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR InterPro; IPR036876; UVR_dom_sf.
DR InterPro; IPR004807; UvrB.
DR InterPro; IPR041471; UvrB_inter.
DR InterPro; IPR024759; UvrB_YAD/RRR_dom.
DR PANTHER; PTHR24029; UVRABC SYSTEM PROTEIN B; 1.
DR PANTHER; PTHR24029:SF0; UVRABC SYSTEM PROTEIN B; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF04851; ResIII; 1.
DR Pfam; PF02151; UVR; 1.
DR Pfam; PF12344; UvrB; 1.
DR Pfam; PF17757; UvrB_inter; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF46600; C-terminal UvrC-binding domain of UvrB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50151; UVR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU003587};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769,
KW ECO:0000256|RuleBase:RU003587};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|RuleBase:RU003587};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881,
KW ECO:0000256|RuleBase:RU003587};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW SOS response {ECO:0000256|RuleBase:RU003587}.
FT DOMAIN 24..165
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 452..614
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 654..689
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
SQ SEQUENCE 689 AA; 79145 MW; 2F555FD8E6FF1AA9 CRC64;
MQFKLKSAFK PTGDQPQAIE KLTSRLGNQL KDQVLLGVTG SGKTFTMANV IENTQLPTLI
ITHNKTLAGQ LYQEMRDFFP ENAVSYFVSY YDYYQPEAYI PTSDTYIEKE AQINQMIDKL
RLQSTTNIMT RRDVIVVASV SCIYNIGDPR EYGKFELPIY KGLLTDWKSL ASRLIEMQYD
RSEFEFVRGS FRIRGNNLDL YPAYQDVAYR IAFLENRVID ITPIDPVSGA RLVDEKIDAG
GIVIYPAKHY MLRQERFQEV EAEIRQDLAK EHQALKAKGK LLEAQRLLER TNYDLEILSE
LGYVNGIENY SRYFDSRQIG DRPYALQDYF NHAYQNNWLT IIDESHMTIP QLRGMYNGDN
SRKRTLVDFG FRLKAALDNR PLKFTEFLPL SPRLIYVSAT PSDWELQLAK KDLIESGILP
SGLNDSDYTV EQLVRPTGIV DPIIEVRPAD TQIQDIIKEV VTRAKAGERS LITTLTKKTA
EDLTQFLTEK GIRANYLHSD IKTLERSDIL DNLRQNKFDC LIGVNLLREG LDLPEVTLVA
ILDADKEGFL RSRVSLIQTM GRAARNIRGS AILYADHITD SMKSAIDEIT RRRDYQLEYN
STHKVTPKNI IKPVRIKIVE ESDQDPASLF IAKERTAKQV QQIDTTSLTA YDREKLVKKL
TRNMKRYATD LNFEAAIAIR DKLRELKGK
//
