ID A0A0G1X189_9BACT Unreviewed; 775 AA.
AC A0A0G1X189;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KKU96343.1};
GN ORFNames=UY27_C0001G0036 {ECO:0000313|EMBL:KKU96343.1};
OS Candidatus Gottesmanbacteria bacterium GW2011_GWA1_48_13.
OC Bacteria; Candidatus Gottesmanbacteria.
OX NCBI_TaxID=1618439 {ECO:0000313|EMBL:KKU96343.1, ECO:0000313|Proteomes:UP000034661};
RN [1] {ECO:0000313|EMBL:KKU96343.1, ECO:0000313|Proteomes:UP000034661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- SIMILARITY: Belongs to the hexokinase family.
CC {ECO:0000256|ARBA:ARBA00009225}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKU96343.1}.
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DR EMBL; LCPJ01000001; KKU96343.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1X189; -.
DR UniPathway; UPA00109; UER00180.
DR Proteomes; UP000034661; Unassembled WGS sequence.
DR GO; GO:0004555; F:alpha,alpha-trehalase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR GO; GO:0004396; F:hexokinase activity; IEA:InterPro.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0001678; P:intracellular glucose homeostasis; IEA:InterPro.
DR GO; GO:0005991; P:trehalose metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.40.367.20; -; 2.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR001661; Glyco_hydro_37.
DR InterPro; IPR001312; Hexokinase.
DR InterPro; IPR022673; Hexokinase_C.
DR InterPro; IPR022672; Hexokinase_N.
DR PANTHER; PTHR23403:SF6; CYTOSOLIC NEUTRAL TREHALASE-RELATED; 1.
DR PANTHER; PTHR23403; TREHALASE; 1.
DR Pfam; PF00349; Hexokinase_1; 1.
DR Pfam; PF03727; Hexokinase_2; 1.
DR Pfam; PF01204; Trehalase; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
DR PROSITE; PS51748; HEXOKINASE_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 400..569
FT /note="Hexokinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00349"
FT DOMAIN 582..674
FT /note="Hexokinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03727"
SQ SEQUENCE 775 AA; 87347 MW; E7AE6F7E9C620F80 CRC64;
MDYQSLIQEI KKVLAPYKAS VKRPAKGALI YDYLVPGSIY QEQWDWDAFF MGVALAAEIP
SEAIYLRNIM LNFMHSARED GYVPGCVTPK GPDIRLNQVK PFVAQGVYLS SRFLGDYDWI
SPYYHTLKKV VLYRENNLWN KKYDLGVWFN SMESGVDNNV SALEFLDKTV VATDINTHVS
REYKSMSFIA SELGRNTDAK FFRERAEHVR ININKYLWDD KDQSYYNLDS TIGNLIRRMT
FSNFVPLYAS IASEKNGQSM IQRYLLNPKK MWSPYGGRTL AKDDPSYNNV NMIKPHSNWQ
GPVWPIANYF YLHALMRYGF QKEAVVLAER ITKLVLTDIK QTGGMHENYD AETGKPLAAP
NFVSWNLLVG NMLDEAVTGK NPLYLHHEYK KTSELFSRLN RTTLIHTSDA FRDELVKTSQ
GGKTSLPCVV HPMSPAGLRD GSGVSFVIGG TMGKSATWRT TDSRVQIEKT AIFALPAVSK
KDEFFRLLTQ EIKEKQPILQ AGISMAYPLT PELVGEQLDG RVIAFTKENN IEGLQGKLVG
QELEVYLKKH KDITTNVSVA NDTICLLLSG LGRGGSRDFP QIAGVVGTGL NFAFFDDATN
WKNRLSLNAH TLVAINIESA NFDGFEMSPA GKAIDESSEN PGKAKLEKEV AGAYLYRLYN
WTMKQAYGHK AHLITDTLTL SRIARQKRHE GQVLANQILE RSAQLVAIEL TGILKYLHKT
QGRIEVIMTG SLFWQGEGYK EKVIKWLDIM LPYVTIDFVN VAENDIVGAA ALANL
//
