ID   A0A0G1YQK0_9BACT        Unreviewed;       379 AA.
AC   A0A0G1YQK0;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   08-NOV-2023, entry version 27.
DE   SubName: Full=Cystathionine gamma-synthase {ECO:0000313|EMBL:KKW17282.1};
GN   ORFNames=UY58_C0006G0005 {ECO:0000313|EMBL:KKW17282.1};
OS   Candidatus Magasanikbacteria bacterium GW2011_GWA2_50_22.
OC   Bacteria; Candidatus Magasanikbacteria.
OX   NCBI_TaxID=1619043 {ECO:0000313|EMBL:KKW17282.1, ECO:0000313|Proteomes:UP000033982};
RN   [1] {ECO:0000313|EMBL:KKW17282.1, ECO:0000313|Proteomes:UP000033982}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT   radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|RuleBase:RU362118};
CC   -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC       {ECO:0000256|RuleBase:RU362118}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKW17282.1}.
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DR   EMBL; LCQN01000006; KKW17282.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0G1YQK0; -.
DR   PATRIC; fig|1619043.3.peg.226; -.
DR   Proteomes; UP000033982; Unassembled WGS sequence.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR   CDD; cd00614; CGS_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR11808:SF75; CYSTATHIONINE GAMMA-SYNTHASE; 1.
DR   PANTHER; PTHR11808; TRANS-SULFURATION ENZYME FAMILY MEMBER; 1.
DR   Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR   PIRSF; PIRSF001434; CGS; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR001434-2}.
FT   MOD_RES         195
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ   SEQUENCE   379 AA;  41540 MW;  C4D9285D7D65A11B CRC64;
     MRFKTKLIHT GAKKDTTFNS VTMPIYATST FAFDELGKNK GYDYTRSGNP TRAALEENIA
     ALEGGVGCSI TATGMAAIHT AMLFLKPGDH IIANTDIYGG TYRLFNDVLK PLGYKFSFVD
     MTDLDAVKNS VTANTKMIWI ETPSNPFLHV TDIAGVVAIA KKGKILTIAD NTFLSPYFQR
     PLELGVDIVA HSTTKYLNGH SDVVGGAIVY STKELRERGN FLVNATGVSG SPFDSWLVLR
     GIKTLALRME AHQKNALAIA QFLEGHKNVK RVYYPGLKSH PQQELIKKQM TGFGGIVTFE
     LDTKKVPLKT FFKKLKYFPL AVSLGGVESL IEAPWFMTHA SMDKEGLKNS GITEETVRVS
     AGIEDADDLI EDLENALKG
//