ID A0A0G2A671_9BACT Unreviewed; 318 AA.
AC A0A0G2A671;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 13-SEP-2023, entry version 36.
DE RecName: Full=Transcription antitermination protein NusB {ECO:0000256|HAMAP-Rule:MF_00073};
DE AltName: Full=Antitermination factor NusB {ECO:0000256|HAMAP-Rule:MF_00073};
GN Name=nusB {ECO:0000256|HAMAP-Rule:MF_00073};
GN ORFNames=UY81_C0028G0003 {ECO:0000313|EMBL:KKW36422.1};
OS Candidatus Giovannonibacteria bacterium GW2011_GWA2_53_7.
OC Bacteria; Candidatus Giovannonibacteria.
OX NCBI_TaxID=1618650 {ECO:0000313|EMBL:KKW36422.1, ECO:0000313|Proteomes:UP000034290};
RN [1] {ECO:0000313|EMBL:KKW36422.1, ECO:0000313|Proteomes:UP000034290}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- FUNCTION: Involved in transcription antitermination. Required for
CC transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC {ECO:0000256|HAMAP-Rule:MF_00073}.
CC -!- SIMILARITY: Belongs to the NusB family. {ECO:0000256|ARBA:ARBA00005952,
CC ECO:0000256|HAMAP-Rule:MF_00073}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKW36422.1}.
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DR EMBL; LCRM01000028; KKW36422.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G2A671; -.
DR PATRIC; fig|1618650.3.peg.314; -.
DR Proteomes; UP000034290; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription termination; IEA:UniProtKB-UniRule.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR Gene3D; 1.10.940.10; NusB-like; 1.
DR HAMAP; MF_00073; NusB; 1.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR InterPro; IPR035926; NusB-like_sf.
DR InterPro; IPR011605; NusB_fam.
DR InterPro; IPR006027; NusB_RsmB_TIM44.
DR NCBIfam; TIGR01951; nusB; 1.
DR PANTHER; PTHR11078:SF3; ANTITERMINATION NUSB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11078; N UTILIZATION SUBSTANCE PROTEIN B-RELATED; 1.
DR Pfam; PF00293; NUDIX; 1.
DR Pfam; PF01029; NusB; 1.
DR SUPFAM; SSF55811; Nudix; 1.
DR SUPFAM; SSF48013; NusB-like; 1.
DR PROSITE; PS51462; NUDIX; 1.
PE 3: Inferred from homology;
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00073};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00073};
KW Transcription antitermination {ECO:0000256|ARBA:ARBA00022814,
KW ECO:0000256|HAMAP-Rule:MF_00073};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_00073}.
FT DOMAIN 137..273
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
FT REGION 286..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 318 AA; 35385 MW; 57C3EFF144F87448 CRC64;
MTSDAAAARL TDYSAEFGAR ESDMPFMKQL LQTAIAKQKE IDEVIVRAAP EWPLDRIAAI
DRNILRLGLT ELLFADRAQV PAKVAINEAI ELAKTFGSNS SGRFVNGVLG AVYIELGEPG
KDEGTARKKA AASWKMQVEE LVGAVVYAHE AEKETVYLAL VHDIFGHWTL SKGKLQPGER
APDGVIRKVQ EEIGLAVVVE DVLGENEYIA NDSKATGGKK RRHAMYYLAR APFADLILKR
EGGLDDAQWF PLQAVGDLNF YDDILPVVTR AINILAQKNR DPQVRIENKD VMEDQRPIEN
REETHEASVE QRGGRRHR
//
