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Database: UniProt
Entry: A0A0G2B2C8_9BACT
LinkDB: A0A0G2B2C8_9BACT
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ID   A0A0G2B2C8_9BACT        Unreviewed;       455 AA.
AC   A0A0G2B2C8;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   25-OCT-2017, entry version 17.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=UY99_C0015G0001 {ECO:0000313|EMBL:KKW48062.1};
OS   Parcubacteria group bacterium GW2011_GWA1_59_11.
OC   Bacteria; unclassified Parcubacteria group.
OX   NCBI_TaxID=1618804 {ECO:0000313|EMBL:KKW48062.1, ECO:0000313|Proteomes:UP000033896};
RN   [1] {ECO:0000313|EMBL:KKW48062.1, ECO:0000313|Proteomes:UP000033896}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a
RT   large radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KKW48062.1}.
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DR   EMBL; LCSE01000015; KKW48062.1; -; Genomic_DNA.
DR   EnsemblBacteria; KKW48062; KKW48062; UY99_C0015G0001.
DR   PATRIC; fig|1618804.3.peg.411; -.
DR   Proteomes; UP000033896; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000033896};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033896}.
FT   DOMAIN      151    280       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      363    431       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     159    166       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
FT   COILED      284    315       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   455 AA;  52451 MW;  F00F6FC8AD3B48DC CRC64;
     MVGMELEQLW MVALNEIELQ ISRANFYTWL KNSRLVDKKE GVFYVALPNN FAREWVEAKY
     QKTLLGILRN HDYSVKKLEF VVGGGSAETL APQKVTVADL NRAENRIELD FKVDPESNLN
     PRYTAKNFIV GASNELAYSA ATAIIQEVGT KYNPFFVYGG VGLGKTHLVQ MIGNEIKALY
     GGKIRPRYVS SEKFTSDIVW AIRNKRMEDI KKKYRDVDVL IIDDIQFIGG KEKTEEEFFH
     TFNALYENNK QIIISSDRPP QSIPTLEERL RSRFEGGLIT DIGYPEYEMR MAIIKNKLQE
     SNRELRDEIV DLVARKVKKN IRELVGVVNK IIFYQDVKKT EITEKIAEEI IEKSIRNFAR
     KVSDDHILKS VAEFFNISIS DLIEKGRRKE VVEPRQVAMF LMREILDVSY PYIGEKLGRD
     HTTAIHAVEK INQEIAKNSA LNQKINLIKE VIFKT
//
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