ID A0A0G2GUF3_9EURO Unreviewed; 700 AA.
AC A0A0G2GUF3;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Translation initiation factor eIF2B subunit epsilon {ECO:0000256|ARBA:ARBA00044144};
DE AltName: Full=eIF2B GDP-GTP exchange factor subunit epsilon {ECO:0000256|ARBA:ARBA00044345};
GN ORFNames=UCRPC4_g01354 {ECO:0000313|EMBL:KKY26888.1};
OS Phaeomoniella chlamydospora.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Phaeomoniellales; Phaeomoniellaceae; Phaeomoniella.
OX NCBI_TaxID=158046 {ECO:0000313|EMBL:KKY26888.1, ECO:0000313|Proteomes:UP000053317};
RN [1] {ECO:0000313|EMBL:KKY26888.1, ECO:0000313|Proteomes:UP000053317}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCRPC4 {ECO:0000313|EMBL:KKY26888.1};
RA Lawrence D.P., Travadon R., Rolshausen P.E., Baumgartner K.;
RT "Distinctive expansion of gene families associated with plant cell wall
RT degradation and secondary metabolism in the genomes of grapevine trunk
RT pathogens.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KKY26888.1, ECO:0000313|Proteomes:UP000053317}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCRPC4 {ECO:0000313|EMBL:KKY26888.1};
RA Morales-Cruz A., Amrine K.C., Cantu D.;
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the eIF-2B gamma/epsilon subunits family.
CC {ECO:0000256|ARBA:ARBA00007878}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKY26888.1}.
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DR EMBL; LCWF01000033; KKY26888.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G2GUF3; -.
DR OrthoDB; 5474157at2759; -.
DR Proteomes; UP000053317; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0004475; F:mannose-1-phosphate guanylyltransferase (GTP) activity; IEA:UniProtKB-EC.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0031369; F:translation initiation factor binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0043934; P:sporulation; IEA:UniProt.
DR CDD; cd04197; eIF-2B_epsilon_N; 1.
DR CDD; cd05787; LbH_eIF2B_epsilon; 1.
DR CDD; cd11558; W2_eIF2B_epsilon; 1.
DR Gene3D; 1.25.40.180; -; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 2.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR035543; eIF-2B_epsilon_N.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR InterPro; IPR003307; W2_domain.
DR InterPro; IPR044123; W2_eIF2B_epsilon.
DR PANTHER; PTHR45887; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON; 1.
DR PANTHER; PTHR45887:SF1; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR Pfam; PF02020; W2; 1.
DR SMART; SM00515; eIF5C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
DR PROSITE; PS51363; W2; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Initiation factor {ECO:0000313|EMBL:KKY26888.1};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000053317}.
FT DOMAIN 525..696
FT /note="W2"
FT /evidence="ECO:0000259|PROSITE:PS51363"
SQ SEQUENCE 700 AA; 78124 MW; 1A0699A9EC74DADB CRC64;
MAPKKDKSGS AKSKGAEEDQ EDALQAVVIA DTFETRFAPL TLERPRCLLP LANVPLIEYT
LEYLANAGVQ DVFLYGGAHT DQVEKYIEVS KWKLPTSPFK KFVFLRSMAT SVGDVMRDLD
GKNFITSDFL AVSGDIISNF PIEDALNQHR ARRDKDRNAI MTMLLREGNK TASTSTASGI
PTFVIDPSKD RCLHYEEVRP RAQVHIDPDV LRKEPEIDIR QDLIDCRIDI CTPDVLSLWS
DNFDNQSPRK EFLYGVLKDY ELNGKTIHTY IIKEHYAARV ANLPYYDLLT GDIASRWTYP
ICPDSNLLPW QHFHLRKGHN YQENGVILSR SCVIGNGCLI GSGSSVGDRS VIKDVVIGRG
CQIGKDVQID GAYIWDNATI GDGTRITKAL VADEATIGDR CTIDTGAVLS FGVRISSDIH
ITHGTMITKA PVEDGASVPN DKDVVGANGE GYQYLPEEEV TPILGSKGSQ NSFYSIPEYA
CSNSSLSSAA SSDVSDAESD SFTPSRKESF LTDVSDDSVD GVALERFHHE AVVSLYERMQ
SNTDPEDVRV ELMGLRFSNN SSEHQVRRAV ATALMKHIQS TIDATGPSAA VASVVTTTLK
RYQILIQREG AEHDVEDQVE FMLASQKDLC HRAEGERILL FVAKDLYDRE VFGEEVFIQW
WHDERSSATE EMQKVRETTR QFIEWLENAE EESSEEEDED
//
