ID A0A0G2JLX7_HUMAN Unreviewed; 438 AA.
AC A0A0G2JLX7;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Killer cell immunoglobulin-like receptor 3DL2 {ECO:0000313|Ensembl:ENSP00000478140.1};
GN Name=KIR3DL2 {ECO:0000313|Ensembl:ENSP00000478140.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000478140.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000478140.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
RN [2] {ECO:0000313|Ensembl:ENSP00000478140.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2022) to UniProtKB.
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DR EMBL; GU182338; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GU182340; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KP420437; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A0G2JLX7; -.
DR SMR; A0A0G2JLX7; -.
DR MassIVE; A0A0G2JLX7; -.
DR Ensembl; ENST00000615318.1; ENSP00000484059.1; ENSG00000278710.4.
DR Ensembl; ENST00000622784.1; ENSP00000478140.1; ENSG00000275629.4.
DR Ensembl; ENST00000639511.1; ENSP00000491144.1; ENSG00000284213.1.
DR HGNC; HGNC:6339; KIR3DL2.
DR Proteomes; UP000005640; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd05711; IgC2_D2_LILR_KIR_like; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013151; Immunoglobulin.
DR PANTHER; PTHR11738:SF166; KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 3DL1-RELATED; 1.
DR PANTHER; PTHR11738; MHC CLASS I NK CELL RECEPTOR; 1.
DR Pfam; PF00047; ig; 3.
DR SMART; SM00409; IG; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
PE 1: Evidence at protein level;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|MaxQB:A0A0G2JLX7,
KW ECO:0007829|PeptideAtlas:A0A0G2JLX7};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..438
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014024443"
FT TRANSMEM 322..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 34..118
FT /note="Immunoglobulin subtype"
FT /evidence="ECO:0000259|SMART:SM00409"
FT DOMAIN 129..209
FT /note="Immunoglobulin subtype"
FT /evidence="ECO:0000259|SMART:SM00409"
FT DOMAIN 229..316
FT /note="Immunoglobulin subtype"
FT /evidence="ECO:0000259|SMART:SM00409"
SQ SEQUENCE 438 AA; 48497 MW; F762A7C9BAC3ED9E CRC64;
MSLTVVSMAC VGFFLLQGAW PLMGGQDKPF LSARPSTVVP RGGHVALQCH YRRGFNNFML
YKEDRSHVPI FHGRIFQESF IMGPVTPAHA GTYRCRGSRP HSLTGWSAPS NPLVIMVTGN
HRKPSLLAHP GPLLKSGETV ILQCWSDVMF EHFFLHREGI SEDPSRLVGQ IHDGVSKANF
SIGPLMPVLA GTYRCYGSVP HSPYQLSAPS DPLDIVITGL YEKPSLSAQP GPTVQAGENV
TLSCSSWSSY DIYHLSREGE AHERRLRAVP KVNRTFQADF PLGPATHGGT YRCFGSFHAL
PCVWSNSSDP LLVSVTGICR HLHVLIGTSV VIFLFILLLF FLLYRWCSNK KNAAVMDQEP
AGDRTVNRQD SDEQDPQEVT YAQLDHCVFI QRKISRPSQR PKTPLTDTSV YTELPNAEPR
SKVVSCPRAP QSGLEGVF
//
