ID A0A0G3A818_9ACTN Unreviewed; 399 AA.
AC A0A0G3A818;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:AKJ10038.1};
GN ORFNames=ABB07_08380 {ECO:0000313|EMBL:AKJ10038.1};
OS Streptomyces incarnatus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=665007 {ECO:0000313|EMBL:AKJ10038.1, ECO:0000313|Proteomes:UP000035366};
RN [1] {ECO:0000313|EMBL:AKJ10038.1, ECO:0000313|Proteomes:UP000035366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL8089 {ECO:0000313|Proteomes:UP000035366};
RX PubMed=26159526;
RA Oshima K., Hattori M., Shimizu H., Fukuda K., Nemoto M., Inagaki K.,
RA Tamura T.;
RT "Draft Genome Sequence of Streptomyces incarnatus NRRL8089, which Produces
RT the Nucleoside Antibiotic Sinefungin.";
RL Genome Announc. 3:e00715-e00715(2015).
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
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DR EMBL; CP011497; AKJ10038.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G3A818; -.
DR STRING; 665007.ABB07_08380; -.
DR PATRIC; fig|665007.5.peg.1831; -.
DR Proteomes; UP000035366; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000835; HTH_MarR-typ.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF12802; MarR_2; 1.
DR Pfam; PF00480; ROK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01125; ROK; 1.
PE 3: Inferred from homology;
FT DOMAIN 19..68
FT /note="HTH marR-type"
FT /evidence="ECO:0000259|Pfam:PF12802"
SQ SEQUENCE 399 AA; 40587 MW; DE1520A76A5BD075 CRC64;
METPGSQSSL HRANLERVVR AVRLAGSLTQ AEIARTTGLS AATVSNIVRE LKDGGTVEVT
PTSAGGRRAR SVSLSGDAGI VIGVDFGHTH LRVAIGNLAH QVLAEEAEPL DVDASAAQGF
DRAEELVSRL IAATGVNRSK VAGVGLGVPG PIDVESGTLG STAILPGWGG TKPAEELRER
LGVPVHVDND ANLGALGELV WGSGKGVRDL AYIKVASGVG AGLVIDGKIY RGPGGTAGEI
GHITLDESGP VCRCGNRGCL ETFAAARYVL PLLQPSHGPD LTMEGVVRLA RDGDPGCRRV
IADVGRHIGS GVANLCNLLN PSRVVLGGDL AEAGELVLGP IRESVGRYAI PSAARQLSVL
PGALGGRAEV LGALALALSE MGDSTLLDGS LPVAAPAFT
//
