ID A0A0G3AKB8_9ACTN Unreviewed; 346 AA.
AC A0A0G3AKB8;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:AKJ11339.1};
GN ORFNames=ABB07_15270 {ECO:0000313|EMBL:AKJ11339.1};
OS Streptomyces incarnatus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=665007 {ECO:0000313|EMBL:AKJ11339.1, ECO:0000313|Proteomes:UP000035366};
RN [1] {ECO:0000313|EMBL:AKJ11339.1, ECO:0000313|Proteomes:UP000035366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL8089 {ECO:0000313|Proteomes:UP000035366};
RX PubMed=26159526;
RA Oshima K., Hattori M., Shimizu H., Fukuda K., Nemoto M., Inagaki K.,
RA Tamura T.;
RT "Draft Genome Sequence of Streptomyces incarnatus NRRL8089, which Produces
RT the Nucleoside Antibiotic Sinefungin.";
RL Genome Announc. 3:e00715-e00715(2015).
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DR EMBL; CP011497; AKJ11339.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G3AKB8; -.
DR STRING; 665007.ABB07_15270; -.
DR PATRIC; fig|665007.5.peg.3287; -.
DR Proteomes; UP000035366; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06296; PBP1_CatR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 12..65
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 346 AA; 36827 MW; AC17D665C1B33C90 CRC64;
MKPSKSAETQ TATLAEIARE AGVSAPTVSK VLNGRADVAP ATRTRVEELL RAHGYRRRRA
EASRSPLIDL VFHELESAWA LEVIRGVENV ARDAGLSVVL SESAGRLTPG RTWADQVAAR
RPHGVVLVLS GLDESQRALL TSRSIPFVVM DPAGDPGPDV PSIGATNWQG GLAATRHLVE
LGHTRIGAIS GPSRMMCSRA RVDGYRAALE TAGLPVDPSL VVAGDFHHDA GYRLGLELLR
RPDRPTAVFA GNDLQALGLY EAARELGLRI PEDLSVVGFD DLPVARWVGP PLTTVRQPLT
EMAEAAARLV LELGREPEER GATRVELATS LVVRSSTAAA AAAGRP
//
