ID A0A0G3AY22_9ACTN Unreviewed; 748 AA.
AC A0A0G3AY22;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Membrane protein {ECO:0000313|EMBL:AKJ15804.1};
GN ORFNames=ABB07_39000 {ECO:0000313|EMBL:AKJ15804.1};
OS Streptomyces incarnatus.
OG Plasmid unnamed_1 sequence {ECO:0000313|Proteomes:UP000035366}.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=665007 {ECO:0000313|EMBL:AKJ15804.1, ECO:0000313|Proteomes:UP000035366};
RN [1] {ECO:0000313|EMBL:AKJ15804.1, ECO:0000313|Proteomes:UP000035366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL8089 {ECO:0000313|Proteomes:UP000035366};
RC PLASMID=Plasmid unnamed_1 sequence
RC {ECO:0000313|Proteomes:UP000035366};
RX PubMed=26159526;
RA Oshima K., Hattori M., Shimizu H., Fukuda K., Nemoto M., Inagaki K.,
RA Tamura T.;
RT "Draft Genome Sequence of Streptomyces incarnatus NRRL8089, which Produces
RT the Nucleoside Antibiotic Sinefungin.";
RL Genome Announc. 3:e00715-e00715(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP011498; AKJ15804.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G3AY22; -.
DR PATRIC; fig|665007.5.peg.8301; -.
DR Proteomes; UP000035366; Plasmid unnamed_1 sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Plasmid {ECO:0000313|EMBL:AKJ15804.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 180..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 533..552
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 564..583
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 603..623
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 644..664
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 676..701
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 204..329
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 748 AA; 78281 MW; 5CE68BF9E25DD829 CRC64;
MATFLSSVGR FAFRRRGLVT LLWIAALIGI GVAASSAPTP PADTFSMPGT ESQKAFDLLK
EKFPAANANG ATARVVLRAP QGHKLADPEQ KAKVEDLVAR LGKAPEVVAV SDPFKANAVS
KDGTTGYAIA TYKVAATKLD DKAHNALTDA LDHSRKSGLT VEAGGDAVKL EAGTGGSAEG
IGILVSALVL VLTFGSMIAA GMPLLTALIG VAIGTSAITA LGSTLGLSTT TTTLAMMLGL
AVGIDYALFV ISRYRSELSE GHERRDAAAR AVGTAGTAVV FAGLTVIIAL AGLAVVNVPM
LTKMGLTAAG TVAIAVLIAI TLVPALLGFA PIKVMPRAER RRFYGKPLSA RQQRKADKRA
ARGKPNLGSR WATFVVRRPL TVLLVGVAGL GALALPAADM QLGLPSEGTY AKDTTQRKAY
DMLSESFGAG FNGPLTVTVQ AQDTAAAAAR VGKQLAGIKN VALVSPATTN PERDTAIITV
VPKTGPQDHA TEELVRTIRG MKADFRSADG ASVLVTGQTA LYIDFSKTLD DALLPYLGLV
VGLAFLLLML VFRSVLVPLK AALGFLLSVG AALGAVVAVF QWGWLAKSFG IHQQGQIMST
LPIFMIGVVF GLAMDYEVFL VARMREAYVH GASPSDAVVS GFRYGGRVVT AAAIIMTSVF
SSFILDTNDF VKMMGFSLAA AVLFDAFVVR MALVPALFAL LGRSAWWLPR WLDRLLPNMD
VEGEKLGRLP AAAPIPGPRR EHEPTYAG
//
