ID A0A0G3CL04_9GAMM Unreviewed; 763 AA.
AC A0A0G3CL04;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Metallo-beta-lactamase domain-containing protein {ECO:0000259|SMART:SM00849};
GN ORFNames=QQ39_11400 {ECO:0000313|EMBL:AKJ42614.1};
OS Pragia fontium.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Budviciaceae; Pragia.
OX NCBI_TaxID=82985 {ECO:0000313|EMBL:AKJ42614.1, ECO:0000313|Proteomes:UP000068021};
RN [1] {ECO:0000313|EMBL:AKJ42614.1, ECO:0000313|Proteomes:UP000068021}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=24613 {ECO:0000313|EMBL:AKJ42614.1,
RC ECO:0000313|Proteomes:UP000068021};
RX PubMed=26159528;
RA Snopkova K., Sedlar K., Bosak J., Chaloupkova E., Provaznik I., Smajs D.;
RT "Complete Genome Sequence of Pragia fontium 24613, an Environmental
RT Bacterium from the Family Enterobacteriaceae.";
RL Genome Announc. 3:e00740-15(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP010423; AKJ42614.1; -; Genomic_DNA.
DR RefSeq; WP_047781348.1; NZ_CP010423.1.
DR AlphaFoldDB; A0A0G3CL04; -.
DR STRING; 82985.QQ39_11400; -.
DR KEGG; pfq:QQ39_11400; -.
DR PATRIC; fig|82985.3.peg.2392; -.
DR OrthoDB; 9761531at2; -.
DR Proteomes; UP000068021; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000068021};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 49..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 487..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 518..698
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 763 AA; 87446 MW; AE336403F596850C CRC64;
MYSTLSLDHI AIAAIAGILP LLFMSALPPM FIWWLLAVFA LLAAVFNQAL IRLVAVFLLS
FLWAVLCADQ MVQQVERYAD QSAHIQGKVI SANINAEGQR SVLFQIRQIN GRELSMLEKF
QLPLYFSINK QDIAQQMFAG QLWQGNILFR AVHSRLNQGG YDQQRWAMAN HQPLTGLVKS
AEILDSSLSL RQSLINRIYQ LTEALESQDI LLALAFGERG MIQPDRRQVF LKTGTAHLMA
ISGLHISLAA LFGWGIARGI QFLFSVRYLG PRFPLLVGWG VATLYVWLSG ANPPALRAFF
ALSIWMVLRW HGMNWTPWQV WLRIVALLLI SDPLMVLSDS LWLSCLAVAG IIFWFQWVPL
PAQIGYRYRS IVLWVYLQIA MMILLIPMQI IIFHGISWTA LLGNLVAVPV VSFISVPAIL
SGLLLCWSQP LAVFFWWIAD RSIIITLFLL EKLQHGWETV TEQMILISFS GWLLIICWRL
SLWRCGLFTP WIILLLTLLP LWQRDDENWR IDMLDVGHGL AMVIRQGNRA IIYDTGNRWR
NGSMAEREIL PFLRWHGLTV EGIILSHQDS DHAGGLSDLQ QAYPDAWLRT STLSLGESCQ
QGDSWRWRGL TFYVLWPQSR VERAYNAHSC VIRVSDGRYS ILLTGDLEKA QELSLIRLYG
DKLKSDVMQT PHHGSKTSST ASFIQAVNPK MTLTSVSRYN PWRLPAENVV KRYKKAQVEW
ISTAKFGQVS VLFYKDYYKF LTLRVHFMPR WYHQWFGSSP YNE
//
