ID A0A0G3EPM3_9BURK Unreviewed; 427 AA.
AC A0A0G3EPM3;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=GDP-mannose dehydrogenase {ECO:0000313|EMBL:AKJ69013.1};
GN ORFNames=ABW99_13160 {ECO:0000313|EMBL:AKJ69013.1};
OS Pandoraea thiooxydans.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Pandoraea.
OX NCBI_TaxID=445709 {ECO:0000313|EMBL:AKJ69013.1, ECO:0000313|Proteomes:UP000036700};
RN [1] {ECO:0000313|Proteomes:UP000036700}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25325 {ECO:0000313|Proteomes:UP000036700};
RA Lim Y.L., Ee R., Yong D., How K.Y., Yin W.F., Chan K.G.;
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
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DR EMBL; CP011568; AKJ69013.1; -; Genomic_DNA.
DR RefSeq; WP_047214910.1; NZ_CP014839.1.
DR AlphaFoldDB; A0A0G3EPM3; -.
DR STRING; 445709.ABW99_13160; -.
DR KEGG; ptx:ABW99_13160; -.
DR PATRIC; fig|445709.3.peg.2789; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000036700; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000036700}.
FT DOMAIN 314..414
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 427 AA; 46269 MW; 34CC153A61BC91B2 CRC64;
MHQRKISVVG LGYVGLPVAV AFGNIAPTIG FDINKRRLSE LVAGHDRTNE VDDAALAASN
LTFTDDVAIL RQADFHIVAV PTPVDDAHQP DLTPVIKASE TVGKALKKGD IVVYESTVFP
GVTEEICVPI LERESKLKSG SDFTVGYSPE RINPGDKEHT FSKIKKVVSG QDASTLEIVA
SVYETVVTAG VHKAASIKVA EAAKVIENTQ RDLNIALMNE LALIFDRMGI DTLDVLEAAG
TKWNFLKFKP GLVGGHCIGV DPYYLTHKAE KLGYIPQVIL SGRRINDSMG AFVARQTIKE
MIHAGHQIAG STVTVLGLTF KENCPDLRNS RVIDIIRELE DFGVSVQVCD PEADPLEAED
EYGIRLTPVA DLARSAGIVV AVAHQSFAKW CVADYLALLG EKPVVIDVKG VCDRTAMNSA
GIRFWRL
//
