ID A0A0G3GR10_9CORY Unreviewed; 225 AA.
AC A0A0G3GR10;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN ORFNames=CEPID_05755 {ECO:0000313|EMBL:AKK03015.1};
OS Corynebacterium epidermidicanis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=1050174 {ECO:0000313|EMBL:AKK03015.1, ECO:0000313|Proteomes:UP000035368};
RN [1] {ECO:0000313|EMBL:AKK03015.1, ECO:0000313|Proteomes:UP000035368}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45586 {ECO:0000313|EMBL:AKK03015.1,
RC ECO:0000313|Proteomes:UP000035368};
RA Ruckert C., Albersmeier A., Winkler A., Tauch A.;
RT "Complete genome sequence of Corynebacterium epidermidicanis DSM 45586,
RT isolated from the skin of a dog suffering from pruritus.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
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DR EMBL; CP011541; AKK03015.1; -; Genomic_DNA.
DR RefSeq; WP_047240110.1; NZ_CP011541.1.
DR AlphaFoldDB; A0A0G3GR10; -.
DR STRING; 1050174.CEPID_05755; -.
DR KEGG; cei:CEPID_05755; -.
DR PATRIC; fig|1050174.4.peg.1163; -.
DR OrthoDB; 9792284at2; -.
DR Proteomes; UP000035368; Chromosome.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:AKK03015.1};
KW Protease {ECO:0000313|EMBL:AKK03015.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000035368};
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT DOMAIN 26..221
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 225 AA; 24124 MW; 96F9738EC359060E CRC64;
MTKGFFVVSA ANGWTLSDGS VHPTGFWAEE LTEPHRVFRE AGFDIAIATP GGVAPTVDKL
SLGDKEVEGY LDSIAGELSK PLVLAEVEEA EYDLVFYPGG HGPMEDLATD TNSGALLLKR
LDEGRPVALL CHAPAAALAA ERPDGTNAFT GKQMTGFSNI EEKVNPFALK AQWLLEDRLK
LLGVDYSKAA LPFRPNVVVD GNLFTGQNPQ SATQLAEQLV EALQK
//
