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Database: UniProt
Entry: A0A0G3GTB2_9CORY
LinkDB: A0A0G3GTB2_9CORY
Original site: A0A0G3GTB2_9CORY 
ID   A0A0G3GTB2_9CORY        Unreviewed;       589 AA.
AC   A0A0G3GTB2;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   25-OCT-2017, entry version 17.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:AKK04364.1};
GN   ORFNames=CMUST_00005 {ECO:0000313|EMBL:AKK04364.1};
OS   Corynebacterium mustelae.
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=571915 {ECO:0000313|EMBL:AKK04364.1, ECO:0000313|Proteomes:UP000035199};
RN   [1] {ECO:0000313|Proteomes:UP000035199}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45274 {ECO:0000313|Proteomes:UP000035199};
RA   Ruckert C., Albersmeier A., Winkler A., Tauch A.;
RT   "Complete genome sequence of Corynebacterium mustelae DSM 45274,
RT   isolated from various tissues of a male ferret with lethal sepsis.";
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00735475}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP011542; AKK04364.1; -; Genomic_DNA.
DR   EnsemblBacteria; AKK04364; AKK04364; CMUST_00005.
DR   KEGG; cmv:CMUST_00005; -.
DR   PATRIC; fig|571915.4.peg.1; -.
DR   KO; K02313; -.
DR   Proteomes; UP000035199; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000035199};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035199}.
FT   DOMAIN      281    409       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      493    562       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     289    296       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   589 AA;  65943 MW;  CE0AFECE3280A21E CRC64;
     MVNEIVQIRT QENNGADPFS PQQRAYLGLA KPLALVEGVA LISVPHPRAK EFIESELSGV
     ICQALTKSFG RSYSLAVTVD PENAIQPFEY RVTQQDQPSN PPPMQQPHQP PVSPAEMAAP
     IEAQSNPGGN FSQQFGASPS VSVPQPMGFS SDTDRFSPPV NIPAEMATEQ MGSPVPGGHY
     PIQPHHVQPQ PAAHVSQQQQ YFSNYPQQSD PQQGWGISHA EQVPNPVEAQ PAWRTREQPA
     HNPNREASLN EKYTFDTYVV SDSNKLPTSA AIAVAEKPAR AYNPLFVWGD SGLGKTHLMH
     AIGNYAHQLN PKLRIKYVSS EEFTNDYINS VRDDRQESFK RRYRDLDILM VDDIQFLQGK
     EGTQEEFFHT FNALQQNGKQ IVLSSDRPPK QLTTLEDRLR TRFQAGLIAD IYPPDLETRI
     AILMKKSQAD GISTSRDVLE LIASRFNSSI RELEGAFIRV SAFASLNNKP IDVHTAEAAL
     RDIMPDEQSV EITPDTIMLV TAEFFDISHE QLVSTTKSRP IAHARQLAMY LCRELTELSL
     PKIGELFGGK DHTTVMYADR KIRKEITEKR DTYDEIQKLT SKIKNYGRS
//
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