ID   A0A0G3IY51_9MYCO        Unreviewed;      1053 AA.
AC   A0A0G3IY51;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Cyclase {ECO:0000313|EMBL:AKK30186.1};
GN   ORFNames=AB431_02780 {ECO:0000313|EMBL:AKK30186.1};
OS   Mycobacterium sp. EPa45.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=1545728 {ECO:0000313|EMBL:AKK30186.1, ECO:0000313|Proteomes:UP000035237};
RN   [1] {ECO:0000313|Proteomes:UP000035237}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EPa45 {ECO:0000313|Proteomes:UP000035237};
RA   Kato H., Ogawa N., Ohtsubo Y., Ohshima K., Toyoda A., Yamazoe A., Mori H.,
RA   Maruyama F., Nagata Y., Hattori M., Fujiyama A., Kurokawa K., Tsuda M.;
RT   "Complete Genome Sequence of a Phenanthrene Degrader, Mycobacterium sp.
RT   Strain EPa45, Isolated from a Phenanthrene-Degrading Consortium.";
RL   Genome Announc.0:0-0(2015).
RN   [2] {ECO:0000313|EMBL:AKK30186.1, ECO:0000313|Proteomes:UP000035237}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EPa45 {ECO:0000313|EMBL:AKK30186.1,
RC   ECO:0000313|Proteomes:UP000035237};
RX   PubMed=26184940;
RA   Kato H., Ogawa N., Ohtsubo Y., Oshima K., Toyoda A., Mori H., Nagata Y.,
RA   Kurokawa K., Hattori M., Fujiyama A., Tsuda M.;
RT   "Complete Genome Sequence of a Phenanthrene Degrader, Mycobacterium sp.
RT   Strain EPa45 (NBRC 110737), Isolated from a Phenanthrene-Degrading
RT   Consortium.";
RL   Genome Announc. 3:e00782-15(2015).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP011773; AKK30186.1; -; Genomic_DNA.
DR   RefSeq; WP_047333015.1; NZ_CP011773.1.
DR   AlphaFoldDB; A0A0G3IY51; -.
DR   STRING; 1545728.AB431_02780; -.
DR   KEGG; mye:AB431_02780; -.
DR   PATRIC; fig|1545728.4.peg.564; -.
DR   OrthoDB; 5476461at2; -.
DR   Proteomes; UP000035237; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          36..166
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   1053 AA;  113632 MW;  2D44E2E16DB43509 CRC64;
     MCGSCGAQFH PGANFCSECG ARLTRASLSA EYKQVTVLFA DVVRSMDIAA TLDMERMREI
     ITELVERSAT AARRYGGTVE YTGDGVMALF GAPIALEDHA FRGCLAAMAI QQEAHRLAGD
     VARRDGVALQ LRVGLNSGRV IAGEIGSGAL GYSAIGQHVG MAQRMESAAP PGGVLLSEST
     ARLVEHKTVL ADLEWVHIKG SDKPVAARRL TGIELRHIPA RRTEANLVGR RWEMAAIDAM
     VDRALGRRGS VVNIVGPPGI GKSRTAREAA ALASSRGFEV FWSFCEAHAS DIPFQVVTQL
     LRVSIGVSDL DAASAREKLR AQFIEADSED LLLLDDLLGI ADPEVSLPQI DPGVRKRRLT
     TLINNATLGR TTPTLYIIED AHWVDPVSES MLADFISVIP NTPSMVLITA RTEYSGALLL
     VHEAQTIFLD PLADSDTAEL IDALLGRDPS VGELAAVIAD RAAGNPFFAE EMVRELDQRG
     VLIGEHGSYI CRTAIAEVSV PATVQAAVEA RIDRLSVSGK RMLNAAAVIG IRFEAELVTE
     LGVDPVFDEL IGAELIDPVG FSPQGRYAFR HPLIRAVAYE SQLKSDRAEW HLRVAAAIQA
     HSADALEENA ILIAEHLQAA DELPGAYGWH MRAGAWSTNR DIDAARRSWE RARSIADQLP
     GEDADHLSMR IAPRTMLYAT VGWSPAGEGS LRRFEELREL CNAAGDKVSL AVGMTGAATE
     LLYAGRSREA SPLASEQMAL LESIGDPDPT VGLAFVAFNV WFDAGEFGEL SKWTQAIIDL
     ADDDPARGAG FGLGSPLAAA LAMRGAARWW LGRPQWLEDL HGAVLMAQNG DPETLAAIVT
     WSYGHAITYG ALRVDDSLLR TIEQVVPLVE GTNDVAACMV LYTLAIALLN RDDAGDRRRG
     LEMMRAVREQ FLGIPTLFLV PLADVFIGQE EARSGDRDVG VALIRQGVDV LRRTGRLGYG
     VWGASVLVEA LLDRGHEGDT AEAEEAVDWL THLAADQDWA ILEIMLLRLN ALLARGRGDA
     ISYRQLAMRY CTKVEVVGFD GHIARAKAMV SDG
//