ID A0A0G3XIP8_9SPHN Unreviewed; 482 AA.
AC A0A0G3XIP8;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=UDP-N-acetylmuramate--alanine ligase {ECO:0000313|EMBL:AKM10501.1};
DE EC=6.3.2.8 {ECO:0000313|EMBL:MBB3988689.1};
GN ORFNames=AB433_11880 {ECO:0000313|EMBL:AKM10501.1}, GGR19_000077
GN {ECO:0000313|EMBL:MBB3988689.1};
OS Croceicoccus naphthovorans.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Erythrobacteraceae; Croceicoccus.
OX NCBI_TaxID=1348774 {ECO:0000313|EMBL:AKM10501.1, ECO:0000313|Proteomes:UP000035287};
RN [1] {ECO:0000313|EMBL:AKM10501.1, ECO:0000313|Proteomes:UP000035287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PQ-2 {ECO:0000313|EMBL:AKM10501.1,
RC ECO:0000313|Proteomes:UP000035287};
RA Zeng Y., Huang Y.;
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:MBB3988689.1, ECO:0000313|Proteomes:UP000536420}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 102796 {ECO:0000313|EMBL:MBB3988689.1,
RC ECO:0000313|Proteomes:UP000536420};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP011770; AKM10501.1; -; Genomic_DNA.
DR EMBL; JACIEL010000001; MBB3988689.1; -; Genomic_DNA.
DR RefSeq; WP_047821186.1; NZ_JACIEL010000001.1.
DR AlphaFoldDB; A0A0G3XIP8; -.
DR STRING; 1348774.AB433_11880; -.
DR KEGG; cna:AB433_11880; -.
DR PATRIC; fig|1348774.3.peg.2500; -.
DR OrthoDB; 9804126at2; -.
DR Proteomes; UP000035287; Chromosome.
DR Proteomes; UP000536420; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008763; F:UDP-N-acetylmuramate-L-alanine ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR Gene3D; 3.90.190.20; Mur ligase, C-terminal domain; 1.
DR Gene3D; 3.40.1190.10; Mur-like, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036565; Mur-like_cat_sf.
DR InterPro; IPR004101; Mur_ligase_C.
DR InterPro; IPR036615; Mur_ligase_C_dom_sf.
DR InterPro; IPR013221; Mur_ligase_cen.
DR InterPro; IPR000713; Mur_ligase_N.
DR PANTHER; PTHR43445:SF3; UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE; 1.
DR PANTHER; PTHR43445; UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE-RELATED; 1.
DR Pfam; PF01225; Mur_ligase; 1.
DR Pfam; PF02875; Mur_ligase_C; 1.
DR Pfam; PF08245; Mur_ligase_M; 1.
DR SUPFAM; SSF51984; MurCD N-terminal domain; 1.
DR SUPFAM; SSF53623; MurD-like peptide ligases, catalytic domain; 1.
DR SUPFAM; SSF53244; MurD-like peptide ligases, peptide-binding domain; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW Cell wall biogenesis/degradation {ECO:0000256|ARBA:ARBA00023316};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:AKM10501.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Peptidoglycan synthesis {ECO:0000256|ARBA:ARBA00022984};
KW Reference proteome {ECO:0000313|Proteomes:UP000035287}.
FT DOMAIN 19..117
FT /note="Mur ligase N-terminal catalytic"
FT /evidence="ECO:0000259|Pfam:PF01225"
FT DOMAIN 125..304
FT /note="Mur ligase central"
FT /evidence="ECO:0000259|Pfam:PF08245"
FT DOMAIN 327..403
FT /note="Mur ligase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02875"
SQ SEQUENCE 482 AA; 50143 MW; 3AF05E385D44A837 CRC64;
MTDAPFSQCT DLSGRPFFFC GIGGSGMLPL ACILNARGAI IAGSDRSRDQ GRSAEKFAWL
EHQGIALFPQ DGSGVTSGDQ VLVASAAIED TVPEVARAKE LGCLRASRAE LLSALFNAAP
KSIAIGGTSG KSTVTGMTGW IMDRAGTDPT IMNGAVMKNF VAPDVPFASA RAGRGGVFVS
EVDESDGSIA LYRPSVAVLL NVTLDHKSMD ELRVLFGDFL AASEVAAINA DDPEALALLP
RAKQALTFGI DEPRAQIGVV PGSIADGPVR QAATVIDRHD GSEYPLLLNV PGRHNLSNAL
AAIAGAVCAG VPVGDAVAAL GTFAGLARRF DVLGTSPSGI AVIDDFGHNP DKVRATLRTL
RTHPGRIIAF FQPHGFSPLR QMGRELADVF AEELLPDDRV ILCDPVYFGG TTDKSVGSAE
LCQWIEDAAG GGGVGAEHIP SREACGDRIA EIALPGDRVA VMGARDDTLT VFAKSVLGRL
SA
//
