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Database: UniProt
Entry: A0A0G4B5K0_9BACT
LinkDB: A0A0G4B5K0_9BACT
Original site: A0A0G4B5K0_9BACT 
ID   A0A0G4B5K0_9BACT        Unreviewed;       463 AA.
AC   A0A0G4B5K0;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   05-JUL-2017, entry version 14.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:AKM82257.1};
GN   ORFNames=UT28_C0001G0452 {ECO:0000313|EMBL:AKM82257.1};
OS   Berkelbacteria bacterium GW2011_GWE1_39_12.
OC   Bacteria; Candidatus Berkelbacteria.
OX   NCBI_TaxID=1618337 {ECO:0000313|EMBL:AKM82257.1, ECO:0000313|Proteomes:UP000035648};
RN   [1] {ECO:0000313|EMBL:AKM82257.1, ECO:0000313|Proteomes:UP000035648}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a
RT   large radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP011213; AKM82257.1; -; Genomic_DNA.
DR   EnsemblBacteria; AKM82257; AKM82257; UT28_C0001G0452.
DR   KEGG; bbgw:UT28_C0001G0452; -.
DR   PATRIC; fig|1618337.4.peg.450; -.
DR   KO; K02313; -.
DR   Proteomes; UP000035648; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000035648};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035648}.
FT   DOMAIN      158    292       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      369    438       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     166    173       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   463 AA;  52348 MW;  98B4090348B42CDB CRC64;
     MKTLDEKETW QAALGELEVV FSKANYSTWF KDTFVLEIAE DEITVGVPNA FTKEWLENKY
     HPQIFEVLKK IHPNLKNATY AVATNSARQA PKIDSADNSD INLKPTQSYT PTQIPVADKP
     QPAFNLNAHY SFDNYVVGNS NRLAMATAQA VAANPGTAYN PLFIYGGVGL GKTHLVQAIG
     NEIIAKSPKK KIVYVSCEKF TNDFIASISD KKTNEFKKMY RDADVLMVDD IQFMAGKEGT
     QEEFFHTFNA LHQANRQIVI TSDRVPKAIP QLTDRLSSRF GMGMVADIQP PNLEMRQAIL
     RNKCAEKQCS LTDDVIDYIA QNIESNIREL EGAITRILTY SQMNDVLPSL AITTKALEDI
     ISNKNKIISV EKMLQMTADF FNITTVDLIS AKRNKELVRP RQIVMYLMRH EMSLSYPKIG
     QHLNKKDHTT VIHGVEKIEK EIARDVELHK ELTALKEKMH AFN
//
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