ID   A0A0G4EHD8_VITBC        Unreviewed;      1043 AA.
AC   A0A0G4EHD8;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=GPI ethanolamine phosphate transferase 3 {ECO:0000256|ARBA:ARBA00020841};
GN   ORFNames=Vbra_11738 {ECO:0000313|EMBL:CEL95155.1};
OS   Vitrella brassicaformis (strain CCMP3155).
OC   Eukaryota; Sar; Alveolata; Colpodellida; Vitrellaceae; Vitrella.
OX   NCBI_TaxID=1169540 {ECO:0000313|EMBL:CEL95155.1, ECO:0000313|Proteomes:UP000041254};
RN   [1] {ECO:0000313|EMBL:CEL95155.1, ECO:0000313|Proteomes:UP000041254}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Zhu J., Qi W., Song R.;
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor
CC       biosynthesis. {ECO:0000256|ARBA:ARBA00004687}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
CC       {ECO:0000256|ARBA:ARBA00008695}.
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DR   EMBL; CDMY01000227; CEL95155.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0G4EHD8; -.
DR   STRING; 1169540.A0A0G4EHD8; -.
DR   VEuPathDB; CryptoDB:Vbra_11738; -.
DR   InParanoid; A0A0G4EHD8; -.
DR   OMA; CTINTES; -.
DR   OrthoDB; 5479199at2759; -.
DR   UniPathway; UPA00196; -.
DR   Proteomes; UP000041254; Unassembled WGS sequence.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0051377; F:mannose-ethanolamine phosphotransferase activity; IEA:InterPro.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd16023; GPI_EPT_3; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR002591; Phosphodiest/P_Trfase.
DR   InterPro; IPR037675; PIG-O_N.
DR   InterPro; IPR045687; PIGG/GPI7_C.
DR   InterPro; IPR039524; PIGO/GPI13.
DR   PANTHER; PTHR23071:SF1; GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3; 1.
DR   PANTHER; PTHR23071; PHOSPHATIDYLINOSITOL GLYCAN; 1.
DR   Pfam; PF01663; Phosphodiest; 1.
DR   Pfam; PF19316; PIGO_PIGG; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   GPI-anchor biosynthesis {ECO:0000256|ARBA:ARBA00022502};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000041254};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        477..501
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        521..542
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        587..605
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        611..630
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        687..706
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        861..886
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        916..937
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        957..979
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1000..1021
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          868..1004
FT                   /note="GPI ethanolamine phosphate transferase 2 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19316"
SQ   SEQUENCE   1043 AA;  112881 MW;  716EF52913D9D33F CRC64;
     MAAHIGWSLA FHLVWQIGLL SVGILFFLQG FFLTRYEIKD RSAADTPPAE PLFPDLHQHH
     PSDATGAASW LPAQYRRVVI LIVDGLRWDF ALYQPDLPVT DAGPYHINGL PTIHRLMTEQ
     PHNSRLYRFV ADAPTATTQR LKALTTGSLP TFFEVRDTFE SSALSEDNLV EQVRRQGRGV
     VAMGDETWVD LFPVVENGLS RAFPYPSFDV KDLHTVDDGV MAHIWAEMNK SDWSVLVGHF
     LGVDHVGHKY EVNHPAMREK LTQMDRVLAD TVDRVDDDTL VVLLGDHGQT DDGAHGGALP
     EEVDSALFVY SRRPFSETSM HPSYPSTRTH HDAIPQVDFV PTLALLLGVP IPFGNLGCIT
     PDMLPSVSHI HGAPAGAAGV VGELRYHAEA FYLNAAQVRR YLGRYDEASG KSFADGEHLA
     ALWERVDSHA GRLRRAEWEQ SDGGVADDLR AFIAACRGYL AAVLDAARAQ WTTFDPVALT
     IGVATSLMAV AAQVMFTLSL ARMETTAPAE WPGALPSPLT VLWRACLGLV LTAPLAATLR
     LIGLPTCTGG CLGAGLVGSY MWSAFVKGGR VLSLLPVRVE VTGGGELLVV VCLCACLFSD
     CYSMLEATCV RFLLSSLLLL HLTAAVLRHV ARRALGRPSA AGEHTRPRRL ILGMVGVLCA
     VRLGPSIDQL EAMPGDRPQP SVVIDHPTAA SAVMLVPLAV MLALLWHSCV RRGWVRRCIA
     VAWGLQFAAT AMQMHVEFYQ RTTETSEARE QRLGATLWAL PIHDALVVVL PRIVYALCGI
     QLLACLSFPG RLIQTTNSGS LESQLHALAL VVVGSQVFPS MTLLGASQVT PAASCLIQLP
     LLLTAVHSSR GQREKERRAS STVVLGGLSE LSVGAMVVLV GFAMFFTTGH RMTFNAVPVS
     AAFVGLLKFD INLSPMLVFL HTYCSFILAF CALPAAVVVT TTAKGGSGDR NAAPPVLLVR
     LVRVMASVLV AASLRYVASE VALIILRRHL MVWSVFAPKY LYDGMAMLLL HGLAPLLAIA
     AHRLLSGGGD SARTRHADVC KAA
//