ID   A0A0G4IQC1_PLABS        Unreviewed;       665 AA.
AC   A0A0G4IQC1;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=NAD-dependent epimerase/dehydratase domain-containing protein {ECO:0000259|Pfam:PF01370};
GN   ORFNames=PBRA_000696 {ECO:0000313|EMBL:CEO97351.1}, PLBR_LOCUS4876
GN   {ECO:0000313|EMBL:SPQ97661.1};
OS   Plasmodiophora brassicae (Clubroot disease agent).
OG   Mitochondrion {ECO:0000313|EMBL:SPQ97661.1}.
OC   Eukaryota; Sar; Rhizaria; Endomyxa; Phytomyxea; Plasmodiophorida;
OC   Plasmodiophoridae; Plasmodiophora.
OX   NCBI_TaxID=37360 {ECO:0000313|EMBL:CEO97351.1, ECO:0000313|Proteomes:UP000039324};
RN   [1] {ECO:0000313|EMBL:CEO97351.1, ECO:0000313|Proteomes:UP000039324}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E3 {ECO:0000313|EMBL:CEO97351.1};
RA   Chooi Y.-H.;
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:SPQ97661.1, ECO:0000313|Proteomes:UP000290189}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Fogelqvist J.;
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CDSF01000079; CEO97351.1; -; Genomic_DNA.
DR   EMBL; OVEO01000008; SPQ97661.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0G4IQC1; -.
DR   STRING; 37360.A0A0G4IQC1; -.
DR   EnsemblProtists; CEO97351; CEO97351; PBRA_000696.
DR   OMA; LCRSRMM; -.
DR   OrthoDB; 5483389at2759; -.
DR   Proteomes; UP000039324; Unassembled WGS sequence.
DR   Proteomes; UP000290189; Unassembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0019205; F:nucleobase-containing compound kinase activity; IEA:InterPro.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd22967; DD_AK7; 1.
DR   Gene3D; 1.20.890.10; cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR000850; Adenylat/UMP-CMP_kin.
DR   InterPro; IPR047499; DD_AK7.
DR   InterPro; IPR007858; Dpy-30_motif.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR48079; PROTEIN YEEZ; 1.
DR   PANTHER; PTHR48079:SF6; PROTEIN YEEZ; 1.
DR   Pfam; PF00406; ADK; 1.
DR   Pfam; PF05186; Dpy-30; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   PRINTS; PR00094; ADENYLTKNASE.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Mitochondrion {ECO:0000313|EMBL:SPQ97661.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000039324};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          10..218
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
FT   REGION          416..441
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          559..587
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   665 AA;  72535 MW;  CBD9EC5C1051AED9 CRC64;
     MAESMPVWKV FIHGAHGYLG RHLVAAMDAR RQAWDGGAEP PAVDEEDPST VTRRLVVLDA
     APDQTLEQKI ASADVIVVDV FESVDDALAL IKAVRSLNFT TPKTLICVST ILTWAGGAPD
     QEISEGSYRA RNPAAAFVRH KLVETLAINS SREYLSTFVL CAGVLYGDGE EPLHPVFRQA
     WLCSPPALPV VGAGTNVIPT IHVADLAKLF VRLAERPPVA APSNFLVAVD KARDTQQAIV
     AAISNALGTG QTATLDVGAA ALDDTRPDAA ERLAIMTSQV LVKREASWVA SFEDLEWRSE
     LGLVANVQSI IDEFVQARAL RPIRLAICGP PGSAKSTVAK RVADLLYLPL INIRDVMARA
     KERMGAELVV GKDGKAALPV AAGIVRQELV RNEVRNKGYV LDGYPRSAEE AVALFEGDSK
     PADGDDADKA EEADDEEAAA KKPKIAIMPE RVICMVATEQ AAMARVKENI GTAIAGHSDE
     KGQARRWAAW TKAGLGGDSG PRKYYTDKGI DVYDLDGGAS RTTTDETLLL YVQGGAPFFN
     YHPTEEEIAE RDRLAKEAEE KARLEEEARE RERREQAEQE AKRRAQKEAE YAAQMAELAI
     KERQAVEERA RPLRDYLNEK VLPYVTEGLY EMAKVQPEDP VDFLAEYLFR CSTNRAAQVQ
     STTPS
//