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Database: UniProt
Entry: A0A0H0ZXG8_9MICC
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ID   A0A0H0ZXG8_9MICC        Unreviewed;       478 AA.
AC   A0A0H0ZXG8;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   27-SEP-2017, entry version 20.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AA310_17415 {ECO:0000313|EMBL:KLI89405.1}, ATC04_00650
GN   {ECO:0000313|EMBL:ALQ29197.1};
OS   Arthrobacter sp. YC-RL1.
OC   Bacteria; Actinobacteria; Micrococcales; Micrococcaceae; Arthrobacter.
OX   NCBI_TaxID=1652545 {ECO:0000313|EMBL:KLI89405.1, ECO:0000313|Proteomes:UP000037645};
RN   [1] {ECO:0000313|EMBL:KLI89405.1, ECO:0000313|Proteomes:UP000037645}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YC-RL1 {ECO:0000313|EMBL:KLI89405.1,
RC   ECO:0000313|Proteomes:UP000037645};
RA   Ren L., Shi Y., Jia Y., Yan Y.;
RT   "Genome sequence of Arthrobacter sp. YC-RL1.";
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ALQ29197.1, ECO:0000313|Proteomes:UP000061913}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YC-RL1 {ECO:0000313|EMBL:ALQ29197.1,
RC   ECO:0000313|Proteomes:UP000061913};
RA   Zhang Y., Guo Z.;
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP013297; ALQ29197.1; -; Genomic_DNA.
DR   EMBL; LCYH01000016; KLI89405.1; -; Genomic_DNA.
DR   RefSeq; WP_047120570.1; NZ_LCYH01000016.1.
DR   EnsemblBacteria; ALQ29197; ALQ29197; ATC04_00650.
DR   EnsemblBacteria; KLI89405; KLI89405; AA310_17415.
DR   KEGG; ary:ATC04_00650; -.
DR   PATRIC; fig|1652545.3.peg.3554; -.
DR   KO; K02313; -.
DR   Proteomes; UP000037645; Unassembled WGS sequence.
DR   Proteomes; UP000061913; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000037645,
KW   ECO:0000313|Proteomes:UP000061913};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037645}.
FT   DOMAIN      169    300       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      381    450       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     177    184       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
FT   COILED      450    477       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   478 AA;  53620 MW;  BA36EC4D3D62A181 CRC64;
     MSSDETNSIG SSWRQVIRKI EDDDRVKARH RAFVSLAKPQ GLIGTTLLVA VPNDLTRDML
     QTQLREPLDD ALRAVFQDDI RCAVSVDLSL SDELEAEEPE VQTAPATPPA VTEAPGPRPQ
     PAPQPTPPSN SQEFGRLNPK YIFDTFVIGS SNRFAHAAAV AVAEAPAKAY NPLFIYGDSG
     LGKTHLLHAI GHYARHLYKG IRVRYVNSEE FTNDFINSIR DDEGASFKQT YRNVDILLID
     DIQFLANKDA TQEEFFHTFN ALHNHNKQVV ITSDLPPKQL QGFEDRMRSR FEWGLLTDIQ
     PPELETRIAI LRKKADAENL SAPSDVMEYI ASRISTNIRE LEGALIRVTA FASLNNQPVD
     LALAETVLKD LISDDGAQEI TPSTIIKQTA EYFGLSIEEL NSKSRTRTLV TARQIAMYLL
     RELTEMSLPK IGAELGGRDH TTVIHADRKI RELMAERRAI FNQVTELTNR IKQSQREH
//
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