GenomeNet

Database: UniProt
Entry: A0A0H1A577_9RHIZ
LinkDB: A0A0H1A577_9RHIZ
Original site: A0A0H1A577_9RHIZ 
ID   A0A0H1A577_9RHIZ        Unreviewed;       512 AA.
AC   A0A0H1A577;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   25-OCT-2017, entry version 17.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=XW59_22020 {ECO:0000313|EMBL:KLI92175.1};
OS   Mesorhizobium sp. LC103.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Phyllobacteriaceae; Mesorhizobium.
OX   NCBI_TaxID=1120658 {ECO:0000313|EMBL:KLI92175.1, ECO:0000313|Proteomes:UP000050670};
RN   [1] {ECO:0000313|EMBL:KLI92175.1, ECO:0000313|Proteomes:UP000050670}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LC103 {ECO:0000313|EMBL:KLI92175.1,
RC   ECO:0000313|Proteomes:UP000050670};
RA   Lee M., Gan H.Y., Gan H.M.;
RT   "Whole Genome Sequencing of Six Isolated Bacteria from Oligotrophic
RT   Conditions within Lechuguilla Cave, New Mexico.";
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KLI92175.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; LBCQ01000012; KLI92175.1; -; Genomic_DNA.
DR   RefSeq; WP_047147689.1; NZ_LBCQ01000012.1.
DR   EnsemblBacteria; KLI92175; KLI92175; XW59_22020.
DR   PATRIC; fig|1120658.4.peg.1399; -.
DR   Proteomes; UP000050670; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000050670};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000050670}.
FT   DOMAIN      203    330       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      418    487       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     211    218       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   512 AA;  57412 MW;  5D61C7D5826B6F42 CRC64;
     MQSGIELEAQ IGQPLSKNQI EGNKMTVAVG PEQIFERVNT QLRARLGNDV YSSWFGRMQL
     AETSKGLVRL SVPTAFLRQW INGHYLDTIC DLWKQSAPEV LKVEIVVRSA TRNIRPVCED
     DDAARKPQRQ VIAGAGAVHL NPSRLDKVTP QRPSPIEGAG KQTVLGSPLD GRYTFDSYVE
     GPSNRVAFAA ARAVAESSSN ALRFNPLFLH ASVGLGKTHL LQAIAAEALK RRPQSRVVYL
     TAEYFMWRFA TAIRDNNALT FKEQLRDIDL LIIDDMQFLQ GKSIQHEFCH LINTLLDSAK
     QVVVAGDRPP SELESLEPRV RSRLNGGVAL EMAAPDFQMR LEILKQRYAA ATSEDASLAI
     PEEILVHVAQ TVTGSGRELE GAFNQILFRQ SFEPQISVER VEELLGHMYR TGEPKRVRIE
     DIQRIVARHY NVSKTELLSN RRTRTIVKPR QVAMYLAKVM TPRSLPEIGR RFGGRDHTTV
     LHAVRKIEDL SGADNTMAQE IELLKRLIND QA
//
DBGET integrated database retrieval system