ID   A0A0H1AIN5_9GAMM        Unreviewed;       458 AA.
AC   A0A0H1AIN5;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=cysteine synthase {ECO:0000256|ARBA:ARBA00012681};
DE            EC=2.5.1.47 {ECO:0000256|ARBA:ARBA00012681};
GN   ORFNames=WQ56_14790 {ECO:0000313|EMBL:KLI98606.1};
OS   Luteimonas sp. FCS-9.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Luteimonas.
OX   NCBI_TaxID=1547516 {ECO:0000313|EMBL:KLI98606.1, ECO:0000313|Proteomes:UP000035397};
RN   [1] {ECO:0000313|EMBL:KLI98606.1, ECO:0000313|Proteomes:UP000035397}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FCS-9 {ECO:0000313|EMBL:KLI98606.1,
RC   ECO:0000313|Proteomes:UP000035397};
RA   Bala M., Kumar A., Kaur N., Mathan Kumar R., Kaur G., Singh N.K.,
RA   Mayilraj S.;
RT   "Taxonomic description and genome sequence of Luteimonas oceanisediminis
RT   sp. nov., a novel gammaproteobacteria isolated from a marine sediment.";
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine;
CC         Xref=Rhea:RHEA:14829, ChEBI:CHEBI:29919, ChEBI:CHEBI:30089,
CC         ChEBI:CHEBI:35235, ChEBI:CHEBI:58340; EC=2.5.1.47;
CC         Evidence={ECO:0000256|ARBA:ARBA00000298};
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- PATHWAY: Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine
CC       from L-serine: step 2/2. {ECO:0000256|ARBA:ARBA00004962}.
CC   -!- SIMILARITY: Belongs to the cysteine synthase/cystathionine beta-
CC       synthase family. {ECO:0000256|ARBA:ARBA00007103}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KLI98606.1}.
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DR   EMBL; LASZ01000020; KLI98606.1; -; Genomic_DNA.
DR   RefSeq; WP_047137911.1; NZ_LASZ01000020.1.
DR   AlphaFoldDB; A0A0H1AIN5; -.
DR   STRING; 1547516.WQ56_14790; -.
DR   PATRIC; fig|1547516.3.peg.3097; -.
DR   OrthoDB; 9805733at2; -.
DR   Proteomes; UP000035397; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016765; F:transferase activity, transferring alkyl or aryl (other than methyl) groups; IEA:UniProt.
DR   GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR   CDD; cd01561; CBS_like; 1.
DR   CDD; cd04608; CBS_pair_CBS; 1.
DR   Gene3D; 3.40.50.1100; -; 2.
DR   Gene3D; 3.10.580.10; CBS-domain; 1.
DR   InterPro; IPR046353; CBS_C.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR001216; P-phosphate_BS.
DR   InterPro; IPR001926; TrpB-like_PALP.
DR   InterPro; IPR036052; TrpB-like_PALP_sf.
DR   PANTHER; PTHR10314; CYSTATHIONINE BETA-SYNTHASE; 1.
DR   PANTHER; PTHR10314:SF191; CYSTATHIONINE BETA-SYNTHASE; 1.
DR   Pfam; PF00571; CBS; 2.
DR   Pfam; PF00291; PALP; 1.
DR   SMART; SM00116; CBS; 1.
DR   SUPFAM; SSF54631; CBS-domain pair; 1.
DR   SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR   PROSITE; PS51371; CBS; 1.
DR   PROSITE; PS00901; CYS_SYNTHASE; 1.
PE   3: Inferred from homology;
KW   CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035397}.
FT   DOMAIN          341..398
FT                   /note="CBS"
FT                   /evidence="ECO:0000259|PROSITE:PS51371"
SQ   SEQUENCE   458 AA;  49876 MW;  5C80758871BC94AB CRC64;
     MPIASSVLDL IADTPIVKAR SLDAGVCELY FKLENQNPGG SIKDRIGLSM IEAAEQRGDI
     APGATLVEGT AGNTGIGLAL VAQQKGYKLI LVVPDKMSRE KIFNLKAMGA EVVLTRSDVA
     KGHPEYYQDL AARIAAETPG AYFINQFGNP DNPAAHEHGT GPEILRQMAE VGGLDAIVFG
     CGSSGTMTGL SRCFAQHAPD VELVLADPVG SILAEYINEG TLNEKSGSWM VEGIGEDFLP
     GISDFSRVGQ AYAISDRESF LAARELLQAE GILGGSSTGT LLAAALKYCR AQTRPKKVLV
     FVCDTGNKYL SKLYNDYWML DNGFIEREQH GDLRDLILRP YSRRDTVVLA PGDLLVTAYQ
     RMKLYEISQL PVMEGDRIVG ILDESDVLLH VYGDEARFRD PVSTAMVSKL DFLDVKSPVE
     ALLPVFDRGQ VAIVTDGDRF LGLITRIDLL NYLRRRVQ
//