ID A0A0H1B3Z2_9EURO Unreviewed; 1815 AA.
AC A0A0H1B3Z2;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=U3 small nucleolar RNA-associated protein 10 {ECO:0000256|ARBA:ARBA00015399, ECO:0000256|RuleBase:RU367065};
GN ORFNames=EMPG_10473 {ECO:0000313|EMBL:KLJ06100.1};
OS Blastomyces silverae.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=2060906 {ECO:0000313|EMBL:KLJ06100.1, ECO:0000313|Proteomes:UP000053573};
RN [1] {ECO:0000313|Proteomes:UP000053573}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 139 {ECO:0000313|Proteomes:UP000053573};
RX PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA Clay O.K., Klein B.S., Cuomo C.A.;
RT "The dynamic genome and transcriptome of the human fungal pathogen
RT Blastomyces and close relative Emmonsia.";
RL PLoS Genet. 11:E1005493-E1005493(2015).
CC -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC Involved in ribosome biosynthesis. {ECO:0000256|ARBA:ARBA00025076}.
CC -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome.
CC {ECO:0000256|ARBA:ARBA00011399, ECO:0000256|RuleBase:RU367065}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|RuleBase:RU367065}.
CC -!- SIMILARITY: Belongs to the HEATR1/UTP10 family.
CC {ECO:0000256|ARBA:ARBA00010559, ECO:0000256|RuleBase:RU367065}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLJ06100.1}.
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DR EMBL; LDEV01003295; KLJ06100.1; -; Genomic_DNA.
DR STRING; 2060906.A0A0H1B3Z2; -.
DR OrthoDB; 5480100at2759; -.
DR Proteomes; UP000053573; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR012954; BP28_C_dom.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR022125; U3snoRNP10_N.
DR InterPro; IPR040191; UTP10.
DR PANTHER; PTHR13457; BAP28; 1.
DR PANTHER; PTHR13457:SF1; HEAT REPEAT-CONTAINING PROTEIN 1; 1.
DR Pfam; PF08146; BP28CT; 1.
DR Pfam; PF12397; U3snoRNP10; 1.
DR SMART; SM01036; BP28CT; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367065};
KW Reference proteome {ECO:0000313|Proteomes:UP000053573};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|RuleBase:RU367065};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW ECO:0000256|RuleBase:RU367065};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552,
KW ECO:0000256|RuleBase:RU367065}.
FT DOMAIN 1517..1671
FT /note="BP28 C-terminal"
FT /evidence="ECO:0000259|SMART:SM01036"
FT REPEAT 1776..1814
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ SEQUENCE 1815 AA; 200726 MW; 085ACDB984327104 CRC64;
MASSLAAQLS QIAATSTHQL DLKAQRVTHS KSLLFEQRDA VSQSFDTIYQ ICHEGFQELC
ALDSRFARFR RTIFSEQSKT EDRLEMNAEQ NQELDTVLEE FLALVGGRLL LQPAIKAVEW
LVRRFRVHEY NTAFVLLTFL PYHTTDLFKV LLSILPENLP PAFKVLNPYR RSLTLPPRHP
IVHSASTNKL FFSSLNNYVL QVSKAQAHYQ GLLSFWAGVV TEALANMLDS ASSGRREVER
RNKEDVLLQI LPVLHSGFGL TKVPELIIGC YMLCVVIAKK TSLEDTVLDG LLEAVAGTWT
QETRLAAMTC LSVLAEHKSS QALPRNVIKS IIRFENSLDL ISELRARSSV TALLLGLIHG
CTKDISEQKD LAPLKFVNDI IQRDILEPEA LIQAMVIVLR AANDVQKSGR MVEGSRTILS
EIIQHFTESE SLAPLLQNAI RESSIDINAL EMGLETVLEG NQMPMTIEDV EMEDVADTGE
KEDVFAQSLE GIPKSTKQAS FLEGPHSAVF GQLAHAFVLA TGNKEKQLQF IDLPILNRGS
ALQDTLYLSF LMRFCSGPYP PVSRAAALQL MADCLTENAS SCIAMQATLP YVISALCDSS
ERVRREAASL LAAFARSCAK IKKEDEHKPQ RSWGYNTLYG KTERSKYLRW LSPRDVYRVV
HRALLPALEE YVLDPAQIRN VLESAIRGTS VSGADNTNTP DSELKKSVRL DLFTFLCSHT
IITPLYAVKL RLLKILNRLG KVGSTTRTEE LSPLLDQWKL LTDDDIAKIA NTEQVDVHEL
EEQVLDTVSG KRKNAVDILL SSVTSQSNTL RPAFADAVFK RLSEIWPSLK EDSEVSAADT
FLQMALGLSA GNEGLSNLCR DLLRTVDLSG PILIRFLNKI STAIIDTEPQ APAAKRRRTS
QNNMVAMTTR DPKELSQIIG KVTFILELID GSNPENHPQL LGGLFQTLAA VHHLKLQLQA
EMSYLLSLVL GIMLAIINKA KLSPKHNLDT SAIRADMIID CIRTSQSPQV QNTALLLVAG
LATISPEIIL HSVMPIFTFM GSNVLKKDDE YSALVIDQTI DQVVPPLIQS LRNQKRDVVS
GTSELLLSFT AAFEHIPSHR RLRLFEALIT KLGAGDFLFA VFAMLANRYG TDRDVVGLMT
SLAANTDVEL QLNSYTKYLG LVGDALLPKP NLSRTLLGVG GEDGRDPPRI AADLLQALSH
LLQSTSLKAQ MTKIFTSDDA DVAPIHNLFS RILEQLLALS DTVRANKPVS KACGDALGSL
LGTLSLIDFL DTIEVLLRRP DDDLRRRVLK LLENRLNQSH ERDSASQSRV LAFLPTLVGI
LESSPDVLLK HASVACIDKI AEKYGKKDPT SVVAAAKVVA GENCIGQPDD RIRVIGMLCL
ASVTEVVGEA IIPVLPAVFS RAFGLLKGSL ESNKKNAQLH DAVYSLISAL ITHVPWMISD
DHLKNILCLS FKSASAGLPE DSDENRHEAL NLLARRVDVS ELFKAVESNW SFAVSEGPQA
VGELLEVTSL AIEKNPKSST IKNVPTLAKL LEKALDIRRT QFSQPTKSSY KEDDVNDIES
QVNDMAIKMI YKLNDTVFRP LFVQLTEWAT GGLPKSDGLG RLLRLTTFYK FLGAFFGTLK
SIVTSYSSYI LESTVEILKT ARCNDKDSKG LWLATMQMLR SSFEHDQDAE FWQSPTHLAA
ISGPLVTQLS HSTNQSSLKL ITGEAIPTIV ELAASADSPD NHKELNSAIM KFMRPGVSNT
GRTGGDNPYT RLAAVKCELS LTERLGEEWL ALLPEMLPYI SELMEDDDEN VEKEVRRWIL
AIEEVLGEKL DDMLV
//
