ID A0A0H1B468_9EURO Unreviewed; 875 AA.
AC A0A0H1B468;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Potassium transport protein {ECO:0000256|PIRNR:PIRNR002450};
GN ORFNames=EMPG_10336 {ECO:0000313|EMBL:KLJ06239.1};
OS Blastomyces silverae.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=2060906 {ECO:0000313|EMBL:KLJ06239.1, ECO:0000313|Proteomes:UP000053573};
RN [1] {ECO:0000313|Proteomes:UP000053573}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 139 {ECO:0000313|Proteomes:UP000053573};
RX PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA Clay O.K., Klein B.S., Cuomo C.A.;
RT "The dynamic genome and transcriptome of the human fungal pathogen
RT Blastomyces and close relative Emmonsia.";
RL PLoS Genet. 11:E1005493-E1005493(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TrkH potassium transport family.
CC {ECO:0000256|ARBA:ARBA00009137, ECO:0000256|PIRNR:PIRNR002450}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLJ06239.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LDEV01003234; KLJ06239.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0H1B468; -.
DR STRING; 2060906.A0A0H1B468; -.
DR OrthoDB; 11415at2759; -.
DR Proteomes; UP000053573; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0030007; P:intracellular potassium ion homeostasis; IEA:UniProtKB-UniRule.
DR InterPro; IPR003445; Cat_transpt.
DR InterPro; IPR004773; K/Na_transp_Trk/HKT.
DR InterPro; IPR015958; Trk_fungi.
DR NCBIfam; TIGR00934; 2a38euk; 1.
DR PANTHER; PTHR31064:SF30; HIGH-AFFINITY POTASSIUM TRANSPORT PROTEIN-RELATED; 1.
DR PANTHER; PTHR31064; POTASSIUM TRANSPORT PROTEIN DDB_G0292412-RELATED; 1.
DR Pfam; PF02386; TrkH; 1.
DR PIRSF; PIRSF002450; K+_transpter_TRK; 2.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR002450};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002450};
KW Potassium {ECO:0000256|ARBA:ARBA00022958, ECO:0000256|PIRNR:PIRNR002450};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538,
KW ECO:0000256|PIRNR:PIRNR002450};
KW Reference proteome {ECO:0000313|Proteomes:UP000053573};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|PIRNR:PIRNR002450};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|PIRNR:PIRNR002450};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR002450}.
FT TRANSMEM 43..65
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 102..127
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 439..464
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 505..523
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 574..594
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 639..656
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 702..718
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 730..750
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT REGION 150..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 188..256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 284..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 813..875
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..169
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..250
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..330
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..397
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 815..844
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 875 AA; 97957 MW; 5BE236987D1041AE CRC64;
MSFQSCLAKA RRTYWSSIEG FMEFVQVLES IRSRIPVISS IRLNFLSLHY AYIIACALAC
SVVIYPNGNM RYIDALLFGT GSATQSGLNP IDLNRLFTYQ QVGLWFVSMI TNPIVIHSFV
VFMRLFWFER RFQHVVREAK TLRRIKTRQR TMTRDAWGRE GEETGPNQDR DGMGVRGKQI
VLVRDCDTGQ AQGGSAVPDV VKKSDPESTS DSDKSPKSTP GGGSSSQMEG QTESEERGEA
VNASQSPVAD DSDRRSVEFR TPQYLSPEHH IAFLEHQRRQ TEALRIPSPR EYDRGGVPQT
VDDTDGGDLT RVRTSQSERP PQSSPLSPLT RPSRGRHITI DEPNAVRMRS RTRTFPRTNS
RRGRSQGGQE PDTDFTPSER TRKGTLSSLF RSTSAQGADV DSSPYLSWQP TIGRNSAFVD
LTEAQRNELG GIEYRALKAL AVVLICYFFL FHLLGIICLI PWILRTERFG NIVRAAGVGR
PWWAIFTSGS SFNDQGFALT PNSMVSFYDA VFPLLLLTFL IIIGNTGFPC MLRFIIWVLS
HLVPVGSPAW EELRFLLDHP RRCFTLLFPR AATWWLFGVL VILNGVDVIF FIILDLNDPE
ISRIPGGIRF VDGLFQAAAT RTAGLSVVNL AEIHPAVQVS YMIMMYISVF PIAISVRRTN
VYEEGSLGVY SYPEEEEEDE TLGSKKINYV GAHLRRQLSF DLWYIFLGLF IIAIVEGGRL
DERGENGFSL FAVMFEIISA YGTVGLSLGF PNTNTSLCAQ FKPLSKLIII AMEIRGRHRG
LPYELDRAIL LPSESLNRKE LLDANKRVRR RGSAASTFSG VTGQQALTDP PQQESGSSSA
YQRDGSAGPR WLELTNRPTG AASNRPPLET HHEDV
//
