ID A0A0H1B478_9EURO Unreviewed; 1039 AA.
AC A0A0H1B478;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=WD repeat protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=EMPG_10737 {ECO:0000313|EMBL:KLJ05848.1};
OS Blastomyces silverae.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=2060906 {ECO:0000313|EMBL:KLJ05848.1, ECO:0000313|Proteomes:UP000053573};
RN [1] {ECO:0000313|Proteomes:UP000053573}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 139 {ECO:0000313|Proteomes:UP000053573};
RX PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA Clay O.K., Klein B.S., Cuomo C.A.;
RT "The dynamic genome and transcriptome of the human fungal pathogen
RT Blastomyces and close relative Emmonsia.";
RL PLoS Genet. 11:E1005493-E1005493(2015).
CC -!- SIMILARITY: Belongs to the WD repeat WDR48 family.
CC {ECO:0000256|ARBA:ARBA00006917}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLJ05848.1}.
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DR EMBL; LDEV01003449; KLJ05848.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0H1B478; -.
DR STRING; 2060906.A0A0H1B478; -.
DR OrthoDB; 2786585at2759; -.
DR Proteomes; UP000053573; Unassembled WGS sequence.
DR CDD; cd17041; Ubl_WDR48; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR021772; WDR48/Bun107.
DR PANTHER; PTHR22847; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF11816; DUF3337; 1.
DR Pfam; PF00400; WD40; 4.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000053573};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 19..53
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 95..126
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 139..174
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 228..269
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 64..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 354..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 639..755
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 775..796
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 971..1039
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 639..653
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 661..675
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 730..755
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 777..796
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 977..1010
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1021..1039
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1039 AA; 112394 MW; B65B40E6798CEB04 CRC64;
MARKSSQRVS YVLPMPDCPG GHRLGVNGLA VDPGSSILYS AGRDGVICAW DLNLDLKSGG
VSNPFSSASS GTTSSNAVSD SSSKTAEATT FRRQIQAHTH WINDIVLAQN NSTLVSASSD
TTVRVWRPES QDLQLPPSIG KHGDYVKCLA TPESHSEWVA SGGLDHKIYL WDLNGAGERL
KIDLSEDEFA TKGSVYALST KGSILASGGP ECVVRVWDHR SGKLVTKFVG HTDNVRDILI
NQDGDTIMTA SSDQTVKIWS MTAGRCMHTL TMHNDSVWSL YSDHPQLSVF YSSDRSGLVA
KTDSRRAADF DQGVCVAALQ ENDGVMQVVA AGDYIWTATP KSSINRWNDV DTTAEVDLPP
SSQHRHTSST VSRQSTGDIK PSSEVSESAP SPRRLPRSSI LQLSNAAAAV GGRIVHEMLL
DDGLELVTPL QALPEETIVG QNGLIKHVLL KDRRRALTQD TAGEVVLWDL IKCIPIQSFG
KRHLDDVTSE VDTIDTIANW CTLDTRTGRL SVILESNRCF DGEIYADEAG LDDLSQFKED
QRINLGKWVL RYLFASLIDE EIKRDAAYRQ SLEEKAKETQ GISRLNAPDS IDIPKIVAQG
VAEAGPSSAT RTANGMYHPV TPGLSIGFVT PGGQSSFSDF GNSPLTSTSG VHGGGKDQPD
YFASSANTHT IDSPDPNPKS PVPPEDESQS QLGTSPADTE KEDKPGKRSG SRFGKKFQMS
FPKKLGRTST ETKPIIEEKV EEESDDKSSE KEKVYDENLS GVIEKMRFEY EETLNEHPGQ
PLSTSITPSE ENETPTLTLP RNTAILIQEE HPDSAVPADL YRGTVGTVGA DADMLEKAAP
KWLGEFLLRN TIPFKEVSKV AFSLKPYQDL LPPVVKPDTL STNTNPSRLN ANRMLRAKKI
LAYVAERIDP QNPDDPDANT LKPEEYLELY CQNTLVPHDM TLSTIRTHIW RTGNDMVLLY
KANGKREIPI PGSEAATVSA PASTSASDAK TGNDDSDLPQ KMSTLGVSGA SEANIAGAGV
GGASSVTSAT SRSASGAEI
//
