ID A0A0H2MLS8_VARPD Unreviewed; 305 AA.
AC A0A0H2MLS8;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=L-2-keto-3-deoxyarabonate dehydratase {ECO:0000313|EMBL:KLN57730.1};
DE EC=4.2.1.43 {ECO:0000313|EMBL:KLN57730.1};
GN Name=araD2 {ECO:0000313|EMBL:KLN57730.1};
GN ORFNames=VPARA_12430 {ECO:0000313|EMBL:KLN57730.1};
OS Variovorax paradoxus.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=34073 {ECO:0000313|EMBL:KLN57730.1, ECO:0000313|Proteomes:UP000035170};
RN [1] {ECO:0000313|EMBL:KLN57730.1, ECO:0000313|Proteomes:UP000035170}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TBEA6 {ECO:0000313|EMBL:KLN57730.1,
RC ECO:0000313|Proteomes:UP000035170};
RA Poehlein A., Schuldes J., Wuebbeler J.H., Hiessl S., Steinbuechel A.,
RA Daniel R.;
RT "Genome sequence of Variovorax paradoxus TBEA6.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLN57730.1}.
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DR EMBL; JZWI01000006; KLN57730.1; -; Genomic_DNA.
DR RefSeq; WP_047783731.1; NZ_JZWI01000006.1.
DR AlphaFoldDB; A0A0H2MLS8; -.
DR PATRIC; fig|34073.19.peg.1265; -.
DR Proteomes; UP000035170; Unassembled WGS sequence.
DR GO; GO:0047449; F:2-dehydro-3-deoxy-L-arabinonate dehydratase activity; IEA:UniProtKB-EC.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF73; 4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000035170}.
FT BINDING 212
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 305 AA; 33476 MW; 001FBA0F73459F4E CRC64;
MTPRYRGIFP VVPTTFTEQG ALDLESQKRC VDFMIDAGSD GLCILANFSE QFVLSDEERE
VLTRTVLEHV AGRVPVIVTT THYSTRICAE RSRRAQDMGA AMLMVMPPYH GATFRVPEPR
IFEFYAGLSD AVNIPIMVQD APASGTLLSA PFLACMAREI EHVAYFKIET AGAASKLREL
IRLGGDAVEG PWDGEEAITL MPDLDAGATG SMTGGGYPDG IRPIIEAHRA GDRDKAFALY
QQWLPLINYE NRQAGLLACK SLMKEGGVIA CEAPRHPLPA MHPETRAGLI ETAKRLDPMV
LRWGR
//
