ID A0A0H3J3Y5_CLOPA Unreviewed; 287 AA.
AC A0A0H3J3Y5;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Catalytic domain-containing protein {ECO:0000313|EMBL:KRU11371.1};
DE SubName: Full=Dihydrolipoyllysine-residue acetyltransferase component of pyruvatedehydrogenase complex {ECO:0000313|EMBL:AJA52619.1};
GN ORFNames=CLPA_c25620 {ECO:0000313|EMBL:AJA52619.1}, CP6013_00618
GN {ECO:0000313|EMBL:KRU11371.1};
OS Clostridium pasteurianum DSM 525 = ATCC 6013.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262449 {ECO:0000313|EMBL:AJA52619.1, ECO:0000313|Proteomes:UP000030905};
RN [1] {ECO:0000313|EMBL:AJA52619.1, ECO:0000313|Proteomes:UP000030905}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 525 {ECO:0000313|EMBL:AJA52619.1}, and DSM 525 / ATCC 6013
RC {ECO:0000313|Proteomes:UP000030905};
RX PubMed=25700415;
RA Poehlein A., Grosse-Honebrink A., Zhang Y., Minton N.P., Daniel R.;
RT "Complete Genome Sequence of the Nitrogen-Fixing and Solvent-Producing
RT Clostridium pasteurianum DSM 525.";
RL Genome Announc. 3:e01591-e01514(2015).
RN [2] {ECO:0000313|EMBL:KRU11371.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 6013 {ECO:0000313|EMBL:KRU11371.1};
RA Pyne M.E., Utturkar S.M., Brown S.D., Moo-Young M., Chung D.A., Chou P.C.;
RT "Improved Draft Genome Sequence of Clostridium pasteurianum Strain ATCC
RT 6013 (DSM 525) Using a Hybrid Next-Generation Sequencing Approach.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KRU11371.1, ECO:0000313|Proteomes:UP000028042}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6013 {ECO:0000313|EMBL:KRU11371.1,
RC ECO:0000313|Proteomes:UP000028042};
RX PubMed=25103768;
RA Pyne M.E., Utturkar S., Brown S.D., Moo-Young M., Chung D.A., Chou C.P.;
RT "Improved Draft Genome Sequence of Clostridium pasteurianum Strain ATCC
RT 6013 (DSM 525) Using a Hybrid Next-Generation Sequencing Approach.";
RL Genome Announc. 2:0-0(0).
CC -!- COFACTOR:
CC Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC Evidence={ECO:0000256|ARBA:ARBA00001938};
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DR EMBL; CP009268; AJA52619.1; -; Genomic_DNA.
DR EMBL; JPGY02000001; KRU11371.1; -; Genomic_DNA.
DR RefSeq; WP_003447385.1; NZ_JPGY02000001.1.
DR AlphaFoldDB; A0A0H3J3Y5; -.
DR GeneID; 76626952; -.
DR KEGG; cpae:CPAST_c25620; -.
DR KEGG; cpat:CLPA_c25620; -.
DR PATRIC; fig|1262449.3.peg.3472; -.
DR eggNOG; COG0508; Bacteria.
DR Proteomes; UP000028042; Unassembled WGS sequence.
DR Proteomes; UP000030905; Chromosome.
DR GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR PANTHER; PTHR43178; DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX; 1.
DR PANTHER; PTHR43178:SF5; LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL; 1.
DR Pfam; PF00198; 2-oxoacid_dh; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 1.
PE 4: Predicted;
KW Pyruvate {ECO:0000313|EMBL:AJA52619.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000030905};
KW Transferase {ECO:0000313|EMBL:AJA52619.1}.
FT DOMAIN 10..151
FT /note="2-oxoacid dehydrogenase acyltransferase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00198"
FT DOMAIN 182..283
FT /note="2-oxoacid dehydrogenase acyltransferase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00198"
SQ SEQUENCE 287 AA; 32605 MW; 5375A6E455A35504 CRC64;
MTNNNIKIKK SIPFDAKRKI VAHATGESWY NIPHITYNYE PDITNFYEEF VELSKKLKSE
GKKISFNSLM IKVISEGLLS AADLNSYLEY DHEKCDGTLH ILDEINIAIP WILSDGSHIT
PSIMNAGKLS LEEISDYISN LTNKINNSDI KEITNILSSE FSSEKPYLEG KEKDNYYKIP
DSERLTKEDF IYGTITFSNI GSLYREQKGS FCLLEVIPPQ VFAIGLSSVQ EKPGVFLDDN
GSKQIGIRKT LPMCLAFDHR ALDFSSIIPF LKKLDSIFDD PSVIHQW
//
