ID A0A0H5CBY5_9PSEU Unreviewed; 405 AA.
AC A0A0H5CBY5;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Polyketide chain length factor WhiE-CLF paralog {ECO:0000313|EMBL:CRK55092.1};
OS Alloactinosynnema sp. L-07.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae.
OX NCBI_TaxID=1653480 {ECO:0000313|EMBL:CRK55092.1, ECO:0000313|Proteomes:UP000076116};
RN [1] {ECO:0000313|Proteomes:UP000076116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L-07 {ECO:0000313|Proteomes:UP000076116};
RA Ramaraj T.;
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Antibiotic biosynthesis. {ECO:0000256|ARBA:ARBA00004792}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
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DR EMBL; LN850107; CRK55092.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0H5CBY5; -.
DR STRING; 1653480.gene:80943945; -.
DR KEGG; alo:CRK55092; -.
DR Proteomes; UP000076116; Chromosome i.
DR GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd00832; CLF; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF322; POLYKETIDE BETA-KETOACYL SYNTHASE 2-RELATED; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Antibiotic biosynthesis {ECO:0000256|ARBA:ARBA00023194};
KW Reference proteome {ECO:0000313|Proteomes:UP000076116};
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 1..399
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 405 AA; 42242 MW; D36428FAD109D520 CRC64;
MVTGLGIVAP TGLGIEEHWQ AVLAGKSGIG RITRFDPSEY PTKLAGEVAG FTAKGRVPGR
LIPQTDHWTH MALFAAESSL ADAGVDPTQL PEFEMAVVTS SSSGGTDFGQ HEMERLYQNG
PSWVGAYQSI AWFYAATTGQ ISIRHGMRGP CGVLCAEQAG GLDAIGQARR LLRTQSQLVV
TGGTDSSLCP YGLVAQLPTG LLSTSDSSDR AYLPFDTEAA GYIPGEGGAI LVTERETTAT
ARGLGKGYGT ILGYAAGFDQ SERTDRKPVL AGVIRRALDD AQLNTSDIDV VFADATADPR
LDRIEADAIT EVFGARGVPV TAPKTLTGRL FGGGAPLDVA TALLALRDGV IPFTAGPNRL
ANGIDIDLVL NTPREASLRH ALVVARGYGG FAAAMVVGKG DRSPA
//
