GenomeNet

Database: UniProt
Entry: A0A0H5CS03_9PSEU
LinkDB: A0A0H5CS03_9PSEU
Original site: A0A0H5CS03_9PSEU 
ID   A0A0H5CS03_9PSEU        Unreviewed;       512 AA.
AC   A0A0H5CS03;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   05-JUL-2017, entry version 19.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
OS   Alloactinosynnema sp. L-07.
OC   Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae.
OX   NCBI_TaxID=1653480 {ECO:0000313|EMBL:CRK60713.1, ECO:0000313|Proteomes:UP000076116};
RN   [1] {ECO:0000313|EMBL:CRK60713.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=L-07 {ECO:0000313|EMBL:CRK60713.1};
RA   Ramaraj Thiru;
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; LN850107; CRK60713.1; -; Genomic_DNA.
DR   RefSeq; WP_054053294.1; NZ_LN850107.1.
DR   EnsemblBacteria; CRK60713; CRK60713; CRK60713.
DR   KEGG; all:CRK60713; -.
DR   KO; K02313; -.
DR   Proteomes; UP000076116; Chromosome i.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000076116};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000076116}.
FT   DOMAIN      204    332       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      416    485       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     212    219       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   512 AA;  56844 MW;  2EF1526ACF31D62C CRC64;
     MSDDQLNLAV VWEQVVRELS AGTLSPSQRA WMRMTRPIGL LDGTALLSAP SDFAKEAIER
     ALREPITDAL SRRLGRSVSL AVKVDVALAP PKPAPPVQAP IQDGLLGEEQ PAAIAVEAPP
     FGDADDDGEE VDEEGDALAT VHEIWPTFTG QQPASGQPFT APAQPQTSKT RLNEKYTFDT
     FVIGASNRFA HAASVAVAEA PARAYNPLFI WGESGLGKTH LLHAVGHYAQ RLFPGMRVRY
     VSTEEFTNDF INSLRDDRKV AFQRRYRDID VLLVDDIQFL EGKEGTQEEF FHTFNTLHNA
     NKQIVVSSDR PPKRLETLED RLRTRFEWGL ITDIQPPELE TRIAILRKKA AQDRLAAPAE
     VLEFIAARVE ANIRELEGAL IRVTAFASLN RQPVDVSLAE IVLRDLIPDS HAPEISAATI
     MAVTAEYFGV SIDDLCGPGK TKALAQARQI SMYLCRELTD LSLPKIGQTF GGRDHTTVMH
     ADKKIRKEMA ERRRVYDQVQ ELTSRIKQRA RG
//
DBGET integrated database retrieval system