ID A0A0H5S1P0_BRUMA Unreviewed; 361 AA.
AC A0A0H5S1P0;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=BMA-SUP-12 {ECO:0000313|EMBL:CRZ22398.1};
GN Name=Bma-sup-12 {ECO:0000313|EMBL:CRZ22398.1};
GN ORFNames=BM_Bm5909 {ECO:0000313|EMBL:CRZ22398.1};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CRZ22398.1};
RN [1] {ECO:0000313|EMBL:CRZ22398.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ22398.1};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CRZ22398.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ22398.1};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LN856393; CRZ22398.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0H5S1P0; -.
DR OMA; MYYPAVT; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12384; RRM_RBM24_RBM38_like; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR48024; GEO13361P1-RELATED; 1.
DR PANTHER; PTHR48024:SF55; RRM DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 118..195
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT COILED 332..359
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 361 AA; 38094 MW; 301819553C928525 CRC64;
MNNLIRVISS SSCAILFCVV CVSLAVPCYF FIFLVKRYLC NVHSLAFLFF SPIARFSSNR
ISACKMIPSI YGQLSNTGTI ADPLVQAAAA ALAAQSAAAT ASATDTLTTT GIRDTTFTKI
FVGGLPYHTS DKTLHEYFEQ FGEIEEAVVI TDRQTQKSRG YGFVTMKDRV AAERACKDPN
PIIDGRKANV NLAYLGAKPR GNIQLAALSN GLQQIPLQTQ LQALFPGRIA GLPQLLYPTA
AAAAAAAAAS NPLMNTLNGL QNTTSLAGAG QVNTSQTQQQ YIDYATLAAV AAAGGATTAT
AQNPFSLHPA VSAAGTVGLE QYAYMPYGLI PANNYAAQLT AAQSQLAAVT QQQAALEHQR
V
//
