ID A0A0H5S1Y4_BRUMA Unreviewed; 476 AA.
AC A0A0H5S1Y4;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Bm135 {ECO:0000313|EMBL:CRZ22209.1};
GN ORFNames=Bm135 {ECO:0000313|EMBL:CRZ22209.1,
GN ECO:0000313|WormBase:Bm135}, BM_Bm135 {ECO:0000313|EMBL:CRZ22209.1};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CRZ22209.1};
RN [1] {ECO:0000313|EMBL:CRZ22209.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ22209.1};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CRZ22209.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ22209.1};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LN856036; CRZ22209.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0H5S1Y4; -.
DR WormBase; Bm135; BM41326; WBGene00220396; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24373; SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN; 1.
DR PANTHER; PTHR24373:SF275; VASORIN; 1.
DR Pfam; PF13855; LRR_8; 3.
DR SMART; SM00365; LRR_SD22; 4.
DR SMART; SM00369; LRR_TYP; 9.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 2.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 358..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 476 AA; 54969 MW; 882263F92B0D1D5D CRC64;
MELYPDIIHL DLSDNNISTF EKNIFRYQNK MELLNLSNNN FSIIFPNNFR GLHRLQYLDL
SFGKLQTIES NAFEHLTELL ELNLSYNALQ NLSFLKFTDL TKLQKLSVAG NQIIYLEDFI
FKTLPNLRAI DLSQNMIKTV ASDTFLGLNM ISLIDLSENF LQEIPIFGQN NLINLEYLNI
GFNKLKKIEP YNFRQLSSIL ELDLTRNEFS LLPASAFDGL FRLKKLKLSE QRYLKQIQNG
AFSGLASLEM LNLSYSYLLE CIDENAFEVS NALHTFDVSF CALKTFPSNL LDWKRVAELQ
LNGNPIHCDH KLLAFLPDIL RLRSIHNVIC ATPDELYNIS ISSLDTVEIT LEDAKRTLII
LCPILIIFTI LIILILFLYS KITPTYDQIK KSKSSIVKQR FCQNLSDKIE CFSPEYYNSI
NEFNSFSVCK SQNTFMNLIQ SKSFYDGISI QIPVNEICTD NDIFLKQTDF IYLSTK
//
