ID A0A0H5S3Y3_BRUMA Unreviewed; 315 AA.
AC A0A0H5S3Y3;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=BMA-SHC-1 {ECO:0000313|EMBL:CRZ23308.1};
DE SubName: Full=SH2 domain containing protein {ECO:0000313|WBParaSite:Bm4335.1};
GN Name=bma-shc-1 {ECO:0000313|WormBase:Bm4335};
GN Synonyms=Bma-shc-1 {ECO:0000313|EMBL:CRZ23308.1,
GN ECO:0000313|WBParaSite:Bm4335.1};
GN ORFNames=Bm4335 {ECO:0000313|WormBase:Bm4335}, BM_Bm4335
GN {ECO:0000313|EMBL:CRZ23308.1};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CRZ23308.1};
RN [1] {ECO:0000313|EMBL:CRZ23308.1, ECO:0000313|Proteomes:UP000006672}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ23308.1,
RC ECO:0000313|Proteomes:UP000006672};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CRZ23308.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ23308.1};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:Bm4335.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2019) to UniProtKB.
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DR EMBL; LN856863; CRZ23308.1; -; Genomic_DNA.
DR STRING; 6279.A0A0H5S3Y3; -.
DR EnsemblMetazoa; Bm4335.1; Bm4335.1; WBGene00224596.
DR WBParaSite; Bm4335.1; Bm4335.1; WBGene00224596.
DR WormBase; Bm4335; BM25029; WBGene00224596; Bma-shc-1.
DR OMA; VKECINM; -.
DR OrthoDB; 2903566at2759; -.
DR Proteomes; UP000006672; Unassembled WGS sequence.
DR CDD; cd00934; PTB; 1.
DR CDD; cd09925; SH2_SHC; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR035676; SHC_SH2.
DR PANTHER; PTHR19969:SF5; ADAPTER MOLECULE CRK; 1.
DR PANTHER; PTHR19969; SH2-SH3 ADAPTOR PROTEIN-RELATED; 1.
DR Pfam; PF00640; PID; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00462; PTB; 1.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS01179; PID; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006672};
KW SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW ProRule:PRU00191}.
FT DOMAIN 25..168
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT DOMAIN 213..305
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
SQ SEQUENCE 315 AA; 36063 MW; 23D06DFA61ED865B CRC64;
MLEDGDVISP SDEELLKELK TGQTFYLKYL GSVQVFESLT KKKPEVRDNW TRHCMYLICH
QLGICNENLR PDEQLLDKLG EVKVEDKNVE LNVALHAFII LDKDGIRILE RHPIHVISYA
SSGTEESTKG VFCFVSHVRE LGRRCLVFME PDKNVDFIME TILQVFRLNN KGHGNKLSIK
MARSSESSSN YDHQTSMNIC NLPAALGLDR QPWYHGEMER ATAESMLRNE GDFLVRISPN
TANNFVLSGI ANSVARHFLL LDENDQKVRK QQQVFETIVE LIEYHRGENV PIISEGSELH
LIRPIVRFTA SLPLR
//
