ID A0A0J0YMI8_9ACTN Unreviewed; 676 AA.
AC A0A0J0YMI8;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN ORFNames=IMCC26207_10433 {ECO:0000313|EMBL:KLR62183.1};
OS Actinobacteria bacterium IMCC26207.
OC Bacteria; Actinomycetota; Actinomycetes.
OX NCBI_TaxID=1641811 {ECO:0000313|EMBL:KLR62183.1, ECO:0000313|Proteomes:UP000036180};
RN [1] {ECO:0000313|EMBL:KLR62183.1, ECO:0000313|Proteomes:UP000036180}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMCC26207 {ECO:0000313|EMBL:KLR62183.1,
RC ECO:0000313|Proteomes:UP000036180};
RA Kim S., Cho J.-C.;
RT "Genome sequence of freshwater Actinobacteria.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLR62183.1}.
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DR EMBL; LCZK01000004; KLR62183.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J0YMI8; -.
DR STRING; 1641811.IMCC26207_10433; -.
DR PATRIC; fig|1641811.3.peg.441; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000036180; Unassembled WGS sequence.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:KLR62183.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000036180}.
FT DOMAIN 45..96
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 105..503
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 556..634
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 676 AA; 74376 MW; 4621C921969C2598 CRC64;
MSDQTNTPDS SATEAATIED YFHENRTFAP SEAFVAAANL SDPTVYATAA QDPEAFWAAQ
ARDSLTWFQD FHTTLEWDLP NAKWFLGGKL NVSYNCLDRH VEAGLGQKVA LHWEGEPGDT
RTLTYSDLLD QVQRFANVLL GLGVQRDDRI CLYMPMIPEA VIAMLACTRI GAIHTLVFGG
FSPDSLVDRI NDAGAVVAIT ADAGYRRGQP SPLKANLDLA LPACPSLRSV VVVDRCGTDI
EMTSGRDHWW DELVSEANPI CPPAHLDSEQ VLYILYTSGT TAKPKGIVHT TGGYLTQAAW
SHRQVFDLKA ESDVYWCAAD VGWVTGHSYI VYGPLTNGAT TVMYEGTPDT PRESERGDDP
TLWPKDRFWD IIERYKVTQL YTAPTAIRTF MKWGEQEPAR HDLSSLRVLG SVGEPINPEA
WMWYHQHIGS ERCPIVDTWW QTETGAHMIT PLPGITATKP GSACAALPGI GVELVDDAGE
VLTVGGGYLT ISQPWPAMLR GIWNAPERYE ETYWSRFPGR YFAGDGAKID EDGYLWLLGR
VDDVMNISGH RISTTEVESA LVDHPAVAEA AVVGASDPTT GQAIVGYVIL RGTFEPSEEL
REQIRRHVDT KLGAIARPRA VIIVPDLPKT RSGKIMRRLL RDVVEGRALG DTTTLADASV
VDAIRERAQA DSSDED
//
