ID   A0A0J1DPB4_9FIRM        Unreviewed;      1412 AA.
AC   A0A0J1DPB4;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=2-hydroxyglutaryl-CoA dehydratase {ECO:0000313|EMBL:KLU40810.1};
GN   ORFNames=AA931_04615 {ECO:0000313|EMBL:KLU40810.1};
OS   Peptococcaceae bacterium 1109.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Peptococcaceae.
OX   NCBI_TaxID=1655638 {ECO:0000313|EMBL:KLU40810.1, ECO:0000313|Proteomes:UP000036486};
RN   [1] {ECO:0000313|EMBL:KLU40810.1, ECO:0000313|Proteomes:UP000036486}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1109 {ECO:0000313|EMBL:KLU40810.1};
RA   Town J.R., Dumonceaux T.J.;
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KLU40810.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LDJB01000001; KLU40810.1; -; Genomic_DNA.
DR   STRING; 1655638.AA931_04615; -.
DR   PATRIC; fig|1655638.3.peg.928; -.
DR   Proteomes; UP000036486; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.420.40; -; 4.
DR   InterPro; IPR002731; ATPase_BadF.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018709; CoA_activase_DUF2229.
DR   InterPro; IPR008275; CoA_E_activase_dom.
DR   NCBIfam; TIGR00241; CoA_E_activ; 1.
DR   PANTHER; PTHR32329:SF4; ACTIVATOR OF 2-HYDROXYACYL-COA DEHYDRATASE-RELATED; 1.
DR   PANTHER; PTHR32329; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR   Pfam; PF01869; BcrAD_BadFG; 2.
DR   Pfam; PF09989; DUF2229; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023014};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00023014}.
FT   DOMAIN          6..254
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          321..575
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          670..890
FT                   /note="DUF2229"
FT                   /evidence="ECO:0000259|Pfam:PF09989"
SQ   SEQUENCE   1412 AA;  154520 MW;  22C8ABC9E061BA05 CRC64;
     MYVSRVGLDV GSTTVKIAVL DDEGRIMYSD YRRHYADIRT SVLALLEAAL MELGNIPVSV
     MVTGSGGIAL AEACGAGFIQ EVIAGTTAIR AVCPDTDVAI ELGGEDAKII YLSDGLEQRM
     NGTCAGGTGA FIDQMAVLLN TDAQGLNELA KSHTTLYPIA ARCGVFAKTD IQPLLNEGAA
     KADIAASVFQ AVVIQTISGL ACGRPIRGNV AFLGGPLHFL SELRKRFIQT LQLKPSQVVF
     PEHSQLINAR GAALASDGRP PVMLAEFIET AQGAVGLTRE EAPRLAPLFA DEESWEDFQR
     AHRAHQVKRG SLADHVGDCY LGIDAGSTTT KLALIDEQGR LLYSYYSSNH GSPLNTAISA
     LLDLYKRLPR ATCLRNAAVT GYGEGLIKAA LKADIGEIET IAHYKGADFF NPGVDFVLDI
     GGQDMKCMRI RDGVIENVLL NEACSSGCGS FLETFAKSLD LSIADFAKAA LTAERPVDLG
     SRCTVFMNSR VKQAQKEGAS VGEISAGLSY SVVKNALFKV IKIRQPEELG ERIVVQGGTF
     YNDAVLRAFE LLTGRRPVRP DIAGLMGAYG AALIAKERCP AGHRSTLLGP KELEQLDVKT
     AKARCGLCGN NCLLTINRFG KDGRFISGNR CERGAGGEPN PRKLPNLYRE RSDRLFAYTP
     LPIEKAPRGR IGIPRVLNIY EDYPFWFTFF TKLGFRVELS PASSKEIYEQ GIDSMPSESV
     CYPGKLAHGH IVSLIDQGCN VIFYPCVPRA RMEQREADNH FNCPIVSSYP EVIKNNVERL
     QEGNIIFLHP FLPLNHKARL SKRLYEELGP TFHLTPGEVE EAVAAAWQEQ ARFRRDVQAM
     GEKALARIQK EGLTGIVLAG RPYHIDSEIH HGIPELINSL GMAVLTEDSV AHLGKVQRPL
     RVVDQWAYHS RLYAAADFVT TQPNLELVQL NSFGCGLDAI TTDQVQEILE AKGKLYTCLK
     IDEGSNLGAA RIRLRSLQAA IRERAQVMPA KSEPYTFPKR LFKKWMRKAH TILAPQMSPI
     HFDLIEAALR HSGYNVEVLP SVDHAAVEEG LKYVNNDSCY PAIIVVGQII SALRSGRYDL
     SNTSVMITQT GGQCRATNYI GLLRRALSDA GFGEIPVISI SAQGLEKSGF KLTPGLIHRA
     IMAVVYGDCL MQLLYRVRPY EAAPGAASNL YHKWAQICKG SLAKVDLRAY AANIRQMVQE
     FDTLPVLPRV KPRVGIVGEI LVKYHPTANN QVVETVENEG AEAVVPGIVD FLNYSLFGLD
     FKYRYLSGTK LGQILANAGI YVLELYRRPL KEALAQSKRF HPPKTIWELA EKAKGVLGLG
     HQAGEGWFLT GEMIELIESG VENIICMQPF ACLPNHVTGK GMIKELKRLY PRANIIAVDY
     DPGASEVNQL NRIKLMLAGA FHNAKHKATS TS
//