ID A0A0J1HH51_9GAMM Unreviewed; 719 AA.
AC A0A0J1HH51;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Tyrosine protein kinase {ECO:0000313|EMBL:KLV10951.1};
DE EC=2.7.10.2 {ECO:0000313|EMBL:KLV10951.1};
GN ORFNames=ABT57_03330 {ECO:0000313|EMBL:KLV10951.1};
OS Photobacterium ganghwense.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Photobacterium.
OX NCBI_TaxID=320778 {ECO:0000313|EMBL:KLV10951.1, ECO:0000313|Proteomes:UP000035909};
RN [1] {ECO:0000313|EMBL:KLV10951.1, ECO:0000313|Proteomes:UP000035909}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22954 {ECO:0000313|EMBL:KLV10951.1,
RC ECO:0000313|Proteomes:UP000035909};
RA Machado H., Gram L.;
RT "Photobacterium galathea sp. nov.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-
CC [protein]; Xref=Rhea:RHEA:10596, Rhea:RHEA-COMP:10136, Rhea:RHEA-
CC COMP:10137, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:46858,
CC ChEBI:CHEBI:82620, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00001074};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the etk/wzc family.
CC {ECO:0000256|ARBA:ARBA00008883}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLV10951.1}.
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DR EMBL; LDOU01000004; KLV10951.1; -; Genomic_DNA.
DR RefSeq; WP_047883788.1; NZ_PYMI01000001.1.
DR AlphaFoldDB; A0A0J1HH51; -.
DR STRING; 320778.ABT57_03330; -.
DR PATRIC; fig|320778.3.peg.715; -.
DR OrthoDB; 9775724at2; -.
DR Proteomes; UP000035909; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0045226; P:extracellular polysaccharide biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05387; BY-kinase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR025669; AAA_dom.
DR InterPro; IPR032807; GNVR.
DR InterPro; IPR003856; LPS_length_determ_N_term.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005702; Wzc-like_C.
DR NCBIfam; TIGR01007; eps_fam; 1.
DR PANTHER; PTHR32309; TYROSINE-PROTEIN KINASE; 1.
DR PANTHER; PTHR32309:SF13; TYROSINE-PROTEIN KINASE ETK-RELATED; 1.
DR Pfam; PF13614; AAA_31; 1.
DR Pfam; PF13807; GNVR; 1.
DR Pfam; PF02706; Wzz; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KLV10951.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000035909};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KLV10951.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Tyrosine-protein kinase {ECO:0000256|ARBA:ARBA00023137}.
FT TRANSMEM 30..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 15..104
FT /note="Polysaccharide chain length determinant N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02706"
FT DOMAIN 367..448
FT /note="Tyrosine kinase G-rich"
FT /evidence="ECO:0000259|Pfam:PF13807"
FT DOMAIN 527..648
FT /note="AAA"
FT /evidence="ECO:0000259|Pfam:PF13614"
SQ SEQUENCE 719 AA; 79433 MW; 08D8F2C36C8D7A1F CRC64;
MSVPHNTQVK QDSAEIDLGK LFGILIDNRW MIIAVTFIFA VVGIAYALMA TPIYKADALI
QVEQKSSGMP ALGDMGELFA SESSATTEIE IIKSRMILGK TVDALNLTTV ATPNYLPIVG
KGLARIQGNK RDIVISRFEV PEYITEPVFE LKVMDGEAGT FALIDANEKT VLDGRVGELA
QQGDFKLFVT ALSAENDAAF TLAKRSRLGA IEWLQQNLSV SERGKQTGIL QLSFTGENRN
EIEEILNDIS QNYFLQNVAR NSAEAENSLQ FLRTHLPDIK AQLTASEDTL NKFRQENESI
DLGLEAKSTL DVMVTIEAQL NELTFKESEI SQRFTREHPA YVALLDKRRT LLGERERLNR
QIQKLPKTQR EVLRMTRDVE VNQQIYVQLL NKVQELNIVK ASTVGNVRIL DAAQSYSRAV
KPKKPLIVVL ATLLGGMLAV AIALLRAAFH RGVENPDEIE AIGLPVYASV PMSDWQIELE
KKQKGKKQLT VNETLLAVSN PADLSIEALR SLRTSLHFAM MEAKNNIIMI SGPSPGIGKS
FVSANMAAVV AKSGSKVLVI DADMRKGRME NQMAVNPKPG LSDFLSGQTD IESLLKKPGV
EGMDFIGRGD VPPNPSELLM HPRFKQLMDW ASENYDIVIV DTPPILAVTD PAIVGAHAGT
TLLVGRFGQN SVKEIEVTKQ RFEQNGIEVK GFILNAVIRK ASSYYGGNYG YYNYSYESK
//
