ID A0A0J5LZN3_PLUGE Unreviewed; 310 AA.
AC A0A0J5LZN3;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=p-hydroxybenzoic acid efflux pump subunit AaeA {ECO:0000256|HAMAP-Rule:MF_01544};
DE Short=pHBA efflux pump protein A {ECO:0000256|HAMAP-Rule:MF_01544};
GN Name=aaeA {ECO:0000256|HAMAP-Rule:MF_01544};
GN ORFNames=ABW06_11265 {ECO:0000313|EMBL:KMK13609.1};
OS Pluralibacter gergoviae (Enterobacter gergoviae).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Pluralibacter.
OX NCBI_TaxID=61647 {ECO:0000313|EMBL:KMK13609.1, ECO:0000313|Proteomes:UP000036196};
RN [1] {ECO:0000313|EMBL:KMK13609.1, ECO:0000313|Proteomes:UP000036196}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JS81F13 {ECO:0000313|EMBL:KMK13609.1,
RC ECO:0000313|Proteomes:UP000036196};
RA Greninger A.L., Miller S.;
RT "Genome sequences of Pluralibacter gergoviae.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Forms an efflux pump with AaeB. {ECO:0000256|HAMAP-
CC Rule:MF_01544}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_01544};
CC Single-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_01544}.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477, ECO:0000256|HAMAP-
CC Rule:MF_01544}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMK13609.1}.
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DR EMBL; LDZF01000010; KMK13609.1; -; Genomic_DNA.
DR RefSeq; WP_048278992.1; NZ_LDZJ01000006.1.
DR AlphaFoldDB; A0A0J5LZN3; -.
DR STRING; 61647.LG71_01350; -.
DR PATRIC; fig|61647.15.peg.373; -.
DR eggNOG; COG1566; Bacteria.
DR Proteomes; UP000036196; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR HAMAP; MF_01544; AaeA; 1.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR022871; PHBA_efflux_pump_AaeA.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30367:SF12; P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT AAEA; 1.
DR PANTHER; PTHR30367; P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT AAEA-RELATED; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF13437; HlyD_3; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_01544};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|HAMAP-Rule:MF_01544};
KW Reference proteome {ECO:0000313|Proteomes:UP000036196};
KW Transmembrane {ECO:0000256|HAMAP-Rule:MF_01544};
KW Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_01544};
KW Transport {ECO:0000256|HAMAP-Rule:MF_01544}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01544"
FT DOMAIN 47..94
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT COILED 117..144
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 310 AA; 34464 MW; 87DDBCFC6A8C4D7A CRC64;
MKALIRKFSR TAITVILVIL AFIAIFHAWV YYTESPWTRD ARFSADVVAI APDVSGLITE
VDVKDNQLVK KGQTLFIIDR PRYQKALAEA DADVAYYQAL ADEKRREAGR RNKIGAVALS
REEVDQANSN LQTVEHQLAR AQATRDLARL DLERTVIRAP SDGWITNLNV YGGEFITRGS
TAVALVKKGT FYVTAYMEET KLEGVRPGYR AEITPLGSTR VLKGTVDSIA SGVTNASSTV
DAKGMATVDS NLEWVRLAQR VPVRIHLDKQ TDNLWPAGTT ATVIVTGKQD RDRGKMNFFQ
KLGMRLREFG
//
