ID A0A0J5MES4_PLUGE Unreviewed; 893 AA.
AC A0A0J5MES4;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=kdpD {ECO:0000313|EMBL:SUB72577.1};
GN ORFNames=ABW06_13595 {ECO:0000313|EMBL:KMK13031.1}, NCTC11434_04053
GN {ECO:0000313|EMBL:SUB72577.1};
OS Pluralibacter gergoviae (Enterobacter gergoviae).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Pluralibacter.
OX NCBI_TaxID=61647 {ECO:0000313|EMBL:KMK13031.1, ECO:0000313|Proteomes:UP000036196};
RN [1] {ECO:0000313|EMBL:KMK13031.1, ECO:0000313|Proteomes:UP000036196}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JS81F13 {ECO:0000313|EMBL:KMK13031.1,
RC ECO:0000313|Proteomes:UP000036196};
RA Greninger A.L., Miller S.;
RT "Genome sequences of Pluralibacter gergoviae.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:SUB72577.1, ECO:0000313|Proteomes:UP000254381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC11434 {ECO:0000313|EMBL:SUB72577.1,
RC ECO:0000313|Proteomes:UP000254381};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; LDZF01000013; KMK13031.1; -; Genomic_DNA.
DR EMBL; UGTG01000002; SUB72577.1; -; Genomic_DNA.
DR RefSeq; WP_048253041.1; NZ_LR699009.1.
DR AlphaFoldDB; A0A0J5MES4; -.
DR STRING; 61647.LG71_21445; -.
DR GeneID; 61384081; -.
DR PATRIC; fig|61647.14.peg.3215; -.
DR eggNOG; COG2205; Bacteria.
DR Proteomes; UP000036196; Unassembled WGS sequence.
DR Proteomes; UP000254381; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF13492; GAF_3; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR Pfam; PF00582; Usp; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000036196};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SUB72577.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 420..439
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..463
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 475..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 668..882
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 893 AA; 97796 MW; 9F7E3E29AE4BAF1D CRC64;
MTDDPLRPDP DRLLADAGRR HRGKLKVFFG ACAGVGKTYA MLSEAQRLRA QGLDIVVGVV
ETHGRRETAA LLDGLATLPP RRQHHRGRKV TEFALDAALA RRPALILMDE LAHTNAAGSR
HPKRWQDVEE LLEAGIDVFT TVNVQHLESL NDVVSGVTGI RVRETVPDPF FDAADDVVLV
DLPADDLRQR LREGKVYIGG QAERAIEHFF RKGNLIALRE LALRRTADRV DSQMRDWRDR
QGEEKVWHTR DAILLCVGHG GGSEKLVRTA ARLAAKLGSA WHAVYVETPD LHRLPEHQRR
SILAALRLAQ ELGAETATLA DPQEDRAILR YAREHNLGKI IIGRRPQRGW RRASFADRLA
RLGPDLDLVI VALEERPPYP GRSSDMRPWH DRWRAQLRGC GVALALCALI TLVASQFLTA
FDAANLVMLY LLGVVIVALR YGRWPSVLAT VVNVVSFDLF FIAPRGTLAV SDVQYVLTFG
VMLTVGLTIG NLTAGVRYQA RVARYREQRT RHLYEMSKAL ARGRSARDIA ATSEAFIQST
FHARSLLLLP DGEDRLAPLT EGAAVAGWDE AIARWSFDKG QPAGAGTDTL PGVPWLSLPL
KTAEKIHGVL IVEPGNRRQL MIPEQQRLLE TCTLLVASAL ERLALTSSEE QARLASERES
VRNALLAALS HDLRTPLTVL FGQAEILTLD LAAAGSPHAA QASEIRQHVL NTARLVNNLL
DMARIQSGGF NLRKEWLTLE EVVGSAIRTL EPGLGGRHIA LSLGDPLTLI HVDGPLFERV
LINLLENAVK YAGPDAQLGI RAAGQPEQLR IEVWDSGPGI PAGQEQAIFA KFARGHKESA
IPGVGLGLAI CQAIVEVHGG TLSAHNRPAG GASFVVTLPP EIPPALDDFT EDA
//
