ID A0A0J5P4N2_PLUGE Unreviewed; 282 AA.
AC A0A0J5P4N2;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=HTH-type transcriptional activator RhaR {ECO:0000256|HAMAP-Rule:MF_01533};
DE AltName: Full=L-rhamnose operon transcriptional activator RhaR {ECO:0000256|HAMAP-Rule:MF_01533};
GN Name=rhaR {ECO:0000256|HAMAP-Rule:MF_01533};
GN ORFNames=ABW06_21340 {ECO:0000313|EMBL:KMK11430.1};
OS Pluralibacter gergoviae (Enterobacter gergoviae).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Pluralibacter.
OX NCBI_TaxID=61647 {ECO:0000313|EMBL:KMK11430.1, ECO:0000313|Proteomes:UP000036196};
RN [1] {ECO:0000313|EMBL:KMK11430.1, ECO:0000313|Proteomes:UP000036196}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JS81F13 {ECO:0000313|EMBL:KMK11430.1,
RC ECO:0000313|Proteomes:UP000036196};
RA Greninger A.L., Miller S.;
RT "Genome sequences of Pluralibacter gergoviae.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Activates expression of the rhaSR operon in response to L-
CC rhamnose. {ECO:0000256|HAMAP-Rule:MF_01533}.
CC -!- SUBUNIT: Binds DNA as a dimer. {ECO:0000256|HAMAP-Rule:MF_01533}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01533}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMK11430.1}.
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DR EMBL; LDZF01000029; KMK11430.1; -; Genomic_DNA.
DR RefSeq; WP_048280505.1; NZ_LDZJ01000025.1.
DR AlphaFoldDB; A0A0J5P4N2; -.
DR STRING; 61647.LG71_04605; -.
DR PATRIC; fig|61647.15.peg.2843; -.
DR eggNOG; COG1917; Bacteria.
DR eggNOG; COG4977; Bacteria.
DR Proteomes; UP000036196; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR GO; GO:0019299; P:rhamnose metabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd06977; cupin_RhaR_RhaS-like_N; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR HAMAP; MF_01533; HTH_type_RhaR; 1.
DR InterPro; IPR003313; AraC-bd.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR037923; HTH-like.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR InterPro; IPR047220; RhaR_RhaS-like_N.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR023699; Tscrpt_act_RhaR.
DR InterPro; IPR020449; Tscrpt_reg_HTH_AraC-type.
DR PANTHER; PTHR46796:SF2; HTH-TYPE TRANSCRIPTIONAL ACTIVATOR RHAS; 1.
DR PANTHER; PTHR46796; HTH-TYPE TRANSCRIPTIONAL ACTIVATOR RHAS-RELATED; 1.
DR Pfam; PF02311; AraC_binding; 1.
DR Pfam; PF12833; HTH_18; 1.
DR PRINTS; PR00032; HTHARAC.
DR SMART; SM00342; HTH_ARAC; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF51215; Regulatory protein AraC; 1.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159, ECO:0000256|HAMAP-Rule:MF_01533};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_01533};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_01533}; Reference proteome {ECO:0000313|Proteomes:UP000036196};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|HAMAP-Rule:MF_01533};
KW Rhamnose metabolism {ECO:0000256|ARBA:ARBA00023308, ECO:0000256|HAMAP-
KW Rule:MF_01533};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_01533};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_01533}.
FT DOMAIN 179..277
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
FT SITE 246
FT /note="Interaction with sigma-70"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01533"
SQ SEQUENCE 282 AA; 32153 MW; C5CF4E028271133C CRC64;
MTAPRILRKS EFFTSPRQAV AVADRYPQDA FAEHTHEFCE LVLVWRGNGL HILNDRPYRI
TRGDLFYICA EDKHSYASVN DLVLQNIIYC PERLTLNVDW AEYIPGLGSA PRVPHWRIGS
SGMAPARQAI AQLEQESSRD SSCSAQMAEL IFAQLVLTLR RHRYATDNQA ATASEALLDK
LLTALAGSIN HPFALEAFCA EQACSERTLR QQFRTQTGMS INHYLRQLRV CHAQYLLRHT
ELMIGEVAMR CGFEDSNYFS VVFNREVGMT PGQWRHHHRN TA
//
