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Database: UniProt
Entry: A0A0J6BKJ3_9SYNE
LinkDB: A0A0J6BKJ3_9SYNE
Original site: A0A0J6BKJ3_9SYNE 
ID   A0A0J6BKJ3_9SYNE        Unreviewed;       464 AA.
AC   A0A0J6BKJ3;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   25-OCT-2017, entry version 19.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=SYNGFB01_05465 {ECO:0000313|EMBL:KMM17232.1};
OS   Synechococcus sp. GFB01.
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae;
OC   Synechococcus.
OX   NCBI_TaxID=1662190 {ECO:0000313|EMBL:KMM17232.1, ECO:0000313|Proteomes:UP000035901};
RN   [1] {ECO:0000313|EMBL:KMM17232.1, ECO:0000313|Proteomes:UP000035901}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GFB01 {ECO:0000313|EMBL:KMM17232.1,
RC   ECO:0000313|Proteomes:UP000035901};
RA   Guimaraes P.I., Leao T.F., de Melo A.G., Ramos R.T., Silva A.,
RA   Fiore M.F., Schneider M.P.;
RT   "Draft genome of the picocyanobacterium Synechococcus sp. strain GFB01
RT   isolated from a freshwater lagoon of the Brazilian Amazon.";
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KMM17232.1}.
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DR   EMBL; LFEK01000033; KMM17232.1; -; Genomic_DNA.
DR   RefSeq; WP_048017277.1; NZ_LFEK01000033.1.
DR   EnsemblBacteria; KMM17232; KMM17232; SYNGFB01_05465.
DR   PATRIC; fig|1662190.3.peg.1648; -.
DR   Proteomes; UP000035901; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000035901};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035901}.
FT   DOMAIN      156    279       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      365    434       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     164    171       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   464 AA;  51330 MW;  8C6E07AAC7A77E2F CRC64;
     MQPDESLWHR IQQALQANLS KPTFETWIRP ARCRSLEDSR LILEAPNSFA CGWLRKHYLD
     TIAAIAAEIA GRAIEVQVHP PAGAGADGAV ALAPVAPSTA TAIAAPAMAV GAGGQSRRRV
     LPALNPRYVF NRFVVGPNSR MAHAAALAVA EAXGREFNPL FLCGGVGLGK THLMQAIGHY
     RLEIDPEARV SYVSTETFTN DLIQAIRKDG MQAFRDRYRA ADLILVDDIQ FIEGKEYTQE
     EFFHTFNALH EAGRQIVIAS DRPPSQIPRL QERLISRFSM GLIADIQAPD LETRMAILHK
     KAEQEQMILP RDLIQFIAGR FTSNIRELEG ALTRAVAFAS ITGLPMTVES VAPMLDPGGG
     DVEVKPELVL EKVAEVFAVA IEEMRSASRK RAVSQARQVG MYLMRQSTNL SLPRIGEVFG
     GKDHSTVMYA VEQVEKRLSL DPSLSRQVQQ VRDLLQIDSR RRKR
//
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