ID A0A0J6YBJ1_COCIT Unreviewed; 772 AA.
AC A0A0J6YBJ1;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Peroxisomal long-chain fatty acid import protein 2 {ECO:0000313|EMBL:KMP05095.1};
GN ORFNames=CIRG_04776 {ECO:0000313|EMBL:KMP05095.1};
OS Coccidioides immitis RMSCC 2394.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=404692 {ECO:0000313|EMBL:KMP05095.1, ECO:0000313|Proteomes:UP000054565};
RN [1] {ECO:0000313|Proteomes:UP000054565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 2394 {ECO:0000313|Proteomes:UP000054565};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCB family.
CC Multidrug resistance exporter (TC 3.A.1.201) subfamily.
CC {ECO:0000256|ARBA:ARBA00007577}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCD family.
CC Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
CC {ECO:0000256|ARBA:ARBA00008575}.
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DR EMBL; DS028095; KMP05095.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J6YBJ1; -.
DR STRING; 404692.A0A0J6YBJ1; -.
DR Proteomes; UP000054565; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03223; ABCD_peroxisomal_ALDP; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11384:SF59; ATP-BINDING CASSETTE SUB-FAMILY D MEMBER; 1.
DR PANTHER; PTHR11384; ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER; 1.
DR Pfam; PF06472; ABC_membrane_2; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 128..342
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 483..717
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT COILED 703..740
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 772 AA; 87133 MW; 5ED14CF7ED5E4286 CRC64;
MAAQSTLRQP EDPLLLLFNH YANLLKSRIQ RSSRRSRLLA TTALLLAIVG SGVERESPGP
KVIAEELWNL EERWSEDHLR AVQVVPFVIR ELQGYDTSYQ VDDLFSLLSI MIPRWNSKET
GLLVSHGVFL MLRTYLSLIV ARLDGEIVRD LVAGKGRAFI WGIIKWCGIG TFASYTNAMI
KFLQSKVSIA FRTRLTRYIH DLYLNDNLNY YKLSNLDGGV GQGADQFITQ DLTLFCTAVS
SLYSSLGKPF VDLVVFTYQL YRSLGPIAFA VIISGYSGTA SLLRRLSPPF GKLKAVEGKK
EGDFRSLHSR ILANAEEIAF YGGADIERVF LSKSFRELQK WMEGIYGLKI RYNMFEDIIL
KYSWSALGYL ITSLPIFLPA WGGLGGMLEM ASTDTSSNRE RGRMKEFITN KRLMLSLADA
GGRMMYSIKD LAELAGYTSR VYTLISTLHR VHANAYYRGR DIQPELYSLS DVQGTIHSGF
DGVRLEHVPI VAPGLFPQGG DELIESLSFI VHSGEHLLVS GPNGVGKSAI ARIVAGLWPV
YRGLVSRPRN FGTDGIMFLP QRPYLSVGTL RDQVIYPHRE MDMRENRRTD AELLQVLEAV
HLGYLPEREG GWDCRKEWKD VLSGGEKQRM AFARLLYHEP RYAFIDEGTS AVSSDVEGLL
YERSKERGIT LITISTRASL KRYHTFNLTL GLGVDGNGWE IDRIGTEKEK MGVEKELQEL
RKRLNNVEDL KRRREEIGNE LQKVWLDDGN QLAPPSYEEA IAVESPDNNT VD
//
