ID   A0A0J6YBN0_COCIT        Unreviewed;       504 AA.
AC   A0A0J6YBN0;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=HMG box domain-containing protein {ECO:0000259|PROSITE:PS50118};
GN   ORFNames=CIRG_03899 {ECO:0000313|EMBL:KMP04208.1};
OS   Coccidioides immitis RMSCC 2394.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=404692 {ECO:0000313|EMBL:KMP04208.1, ECO:0000313|Proteomes:UP000054565};
RN   [1] {ECO:0000313|Proteomes:UP000054565}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RMSCC 2394 {ECO:0000313|Proteomes:UP000054565};
RX   PubMed=20516208; DOI=10.1101/gr.103911.109;
RA   Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA   Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA   Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA   FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA   Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA   Taylor J.W., Rounsley S.D.;
RT   "Population genomic sequencing of Coccidioides fungi reveals recent
RT   hybridization and transposon control.";
RL   Genome Res. 20:938-946(2010).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; DS028094; KMP04208.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0J6YBN0; -.
DR   STRING; 404692.A0A0J6YBN0; -.
DR   Proteomes; UP000054565; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   CDD; cd01389; HMG-box_ROX1-like; 1.
DR   Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR   InterPro; IPR009071; HMG_box_dom.
DR   InterPro; IPR036910; HMG_box_dom_sf.
DR   PANTHER; PTHR45803; SOX100B; 1.
DR   PANTHER; PTHR45803:SF5; SOX100B; 1.
DR   Pfam; PF00505; HMG_box; 1.
DR   SMART; SM00398; HMG; 1.
DR   SUPFAM; SSF47095; HMG-box; 1.
DR   PROSITE; PS50118; HMG_BOX_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00267};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00267}.
FT   DOMAIN          161..229
FT                   /note="HMG box"
FT                   /evidence="ECO:0000259|PROSITE:PS50118"
FT   DNA_BIND        161..229
FT                   /note="HMG box"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT   REGION          63..112
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          221..309
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        73..87
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        279..304
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   504 AA;  56569 MW;  28D0B4CF12893172 CRC64;
     MYARQDYPFA KIDVDNRDVT EVMAGYPQTG AFNSVPGAEF PQITSVPQLT YVRAMQLTGN
     QHHQHHAVDM GRTGSGGSSS SRGSTGMHKF QDADKSRVQR MTRVRKRTRT ARSDKRNLII
     TAPLSVLTKD MVHIPIRDMK AWVNRSAEVR RKEVAAKNGK IARPMNSFML YRSAYAERTK
     EWCAQNNHQV VSRASGQSWP LEPKEIRDLY EGYATIERDN HQKAHPDYKF APNKTQNTPK
     KKQTATKDDE NSDLDDAGFD IPACSRPVGT WPSRSDADEG FGSRTSTPFD KDSSYESRTS
     TPFDHPNGDM YVHHSDINRS SWEMVNPGRP LPGVLSPPEQ SHYYQPSIHQ SVLGPGIEDV
     TYKKMGVPGV SYEPQGTLNG LPGNPHPELL PTQPSRTVED STQVDPQLLE FSHHQQQSVT
     EAGSYPGHLN LWQVPPTTQH YVPTSIPAQQ AEEYLSAHAQ QTGFHHGASL MESRDVWGEG
     HNGEAVKQEF GQEFDQWLTG HHTY
//