ID A0A0J6YPY5_9BACT Unreviewed; 635 AA.
AC A0A0J6YPY5;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Sulfatase N-terminal domain-containing protein {ECO:0000259|Pfam:PF00884};
GN ORFNames=UZ36_06820 {ECO:0000313|EMBL:KMP10686.1};
OS Candidatus Nitromaritima sp. SCGC AAA799-C22.
OC Bacteria; Nitrospinae/Tectomicrobia group; Nitrospinota; Nitrospinia;
OC Nitrospinales; Nitrospinaceae; Candidatus Nitromaritima.
OX NCBI_TaxID=1628279 {ECO:0000313|EMBL:KMP10686.1, ECO:0000313|Proteomes:UP000036407};
RN [1] {ECO:0000313|EMBL:KMP10686.1, ECO:0000313|Proteomes:UP000036407}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCGC_AAA799_C22 {ECO:0000313|EMBL:KMP10686.1};
RA Ngugi D.K., Blom J., Stepanauskas R., Stingl U.;
RT "Diversification and niche adaptations of Nitrospina-like bacteria in the
RT poly-extreme interfaces of the Atlantis II Deep brine from the Red Sea.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMP10686.1}.
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DR EMBL; JZKJ01000048; KMP10686.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J6YPY5; -.
DR PATRIC; fig|1628279.3.peg.1211; -.
DR Proteomes; UP000036407; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16015; LTA_synthase; 1.
DR Gene3D; 3.30.1120.80; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR012160; LtaS-like.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR47371; LIPOTEICHOIC ACID SYNTHASE; 1.
DR PANTHER; PTHR47371:SF3; PHOSPHOGLYCEROL TRANSFERASE I; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR PIRSF; PIRSF005091; Mmb_sulf_HI1246; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Manganese {ECO:0000256|PIRSR:PIRSR005091-2};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR005091-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000036407};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 54..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 277..546
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
FT ACT_SITE 324
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-1"
FT BINDING 284
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 324
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 442
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-2"
FT BINDING 495
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 496
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
SQ SEQUENCE 635 AA; 73326 MW; 2EBC0A4359875E1E CRC64;
MCKTTVTVIG ALFILFALEN LAIRAILTIK EFSSLDTPAW DLFKIFSMGS LSDFLAFSYF
SIPFVLYLTF LPGFLINSRF NKILIHSSFF LFVIFLSFQA HAEWFFWEEF NSRFNFIAVD
YLIYTHEVIG NIMESYPMHW VFVSILCWSL VLYFSTKKLI VRSIEAFRET KISQRLPAFT
LLLSIPAIVF FTMGNIAEDT SRNRIVRELA KNGAYQFFSA FRNNELDYYT FYKTFEDKQV
VEMMRKELSS NNSQWVHSAL GADERVIRHL GPEKKYNVML IVVESLSANY LGTFGNKAGI
TPHLDKLAKE SMLFTHLYAA GNRTVRGLEA ITLSIPPTPG FSLIKQPHNE NLFSLGKLFA
SKGYETKFLY GGFGYFDNMN YFFSHNSFQV IDRTNFDDDE ISFANVWGIA DESLLQKALK
EADLSFEKNR PFLNLIMTTS NHRPYTYPEG RIDLPSKSAG RDGGVKYTDY SIGTFLKAAR
QKPWFDNTLF VIVADHYAGG KGKTEISLPK FHIPMLIYAP KIIKPEIIDT LCNQMDIAPT
LAGLLNFTYK TKFFGKDILQ IKKSDERLLL GTYQFLGYYK EKILVKLSPM KKVEYFSTTP
EEKTGRRVRP NLERLHEAVD YYQYATYLIS HDKYH
//
