ID A0A0J7L328_LASNI Unreviewed; 606 AA.
AC A0A0J7L328;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Trehalase {ECO:0000256|ARBA:ARBA00019905, ECO:0000256|RuleBase:RU361180};
DE EC=3.2.1.28 {ECO:0000256|ARBA:ARBA00012757, ECO:0000256|RuleBase:RU361180};
DE AltName: Full=Alpha-trehalose glucohydrolase {ECO:0000256|RuleBase:RU361180};
GN ORFNames=RF55_2437 {ECO:0000313|EMBL:KMQ97237.1};
OS Lasius niger (Black garden ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Lasius; Lasius.
OX NCBI_TaxID=67767 {ECO:0000313|EMBL:KMQ97237.1, ECO:0000313|Proteomes:UP000036403};
RN [1] {ECO:0000313|EMBL:KMQ97237.1, ECO:0000313|Proteomes:UP000036403}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole {ECO:0000313|EMBL:KMQ97237.1};
RA Konorov E.A., Nikitin M.A., Kirill M.V., Chang P.;
RT "Lasius niger genome sequencing.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-
CC glucose; Xref=Rhea:RHEA:32675, ChEBI:CHEBI:15377, ChEBI:CHEBI:15903,
CC ChEBI:CHEBI:16551, ChEBI:CHEBI:17925; EC=3.2.1.28;
CC Evidence={ECO:0000256|ARBA:ARBA00001576,
CC ECO:0000256|RuleBase:RU361180};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 37 family.
CC {ECO:0000256|ARBA:ARBA00005615, ECO:0000256|RuleBase:RU361180}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMQ97237.1}.
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DR EMBL; LBMM01000908; KMQ97237.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J7L328; -.
DR STRING; 67767.A0A0J7L328; -.
DR PaxDb; 67767-A0A0J7L328; -.
DR OrthoDB; 1329212at2759; -.
DR Proteomes; UP000036403; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004555; F:alpha,alpha-trehalase activity; IEA:UniProtKB-EC.
DR GO; GO:0005991; P:trehalose metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR001661; Glyco_hydro_37.
DR InterPro; IPR018232; Glyco_hydro_37_CS.
DR PANTHER; PTHR23403; TREHALASE; 1.
DR PANTHER; PTHR23403:SF1; TREHALASE; 1.
DR Pfam; PF01204; Trehalase; 1.
DR PRINTS; PR00744; GLHYDRLASE37.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
DR PROSITE; PS00927; TREHALASE_1; 1.
DR PROSITE; PS00928; TREHALASE_2; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000036403};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 543..564
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 606 AA; 70606 MW; 9FC41FFC1F7E95EC CRC64;
MAGVYKDSKH FVDMKMKRSA NETLTSFQVF MRSVNDAPNK HQVEKFINDT FEPPGYEFED
WDPADWTANP KFLQNIEDDE LRKFGSDLNL IWKLLGRKMR DDVRINEHLY SIIYVPHPVI
VPGGRFREFY YWDSYWIIKG LLLSEMHSTV RGMLNNFVSI VDKIGFIPNG GRIYYKMRSH
PPLLTPMVDE YLKVTHDNAW LKENLWLLEK EFDFWMTNRT VDIEVDGTNY TLARYYEESS
GPRPESYKED YLTSQSFRTA EEKDNYYSEL KTAAESGWDF SSRWFVHEGT NKGNLTNLKS
RSIIPVDLNA IIYRNAVLLA QYNRRMGNET KAAYYDYIAE KWKEAIRMVL WHEEVGVWLD
YDILNDIKRD YFYPTNILPL WTDSYDTSKK AEYLSKVLKY LEKNQIMLNH GGIPTTLEHS
GEQWDYPNAW PPLQYFFIMS LNNTGDAWAQ RLAYEISQRW VRSNYKAFNE THSMYEKYDA
TVSGGHGSGG EYEVQLGFGW SNGVVMALLD KYGDKLTAED YFIAGEVVEN AAPPQVISTA
GQMLTGLLAL IISLATGFIG MVMYKRRQYY APGPSTMPNK RQVLSSGSNL YRKRVAYTEL
KDMNND
//
