ID A0A0J7ZNS5_STRVR Unreviewed; 1234 AA.
AC A0A0J7ZNS5;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=nitrate reductase (quinone) {ECO:0000256|ARBA:ARBA00012500};
DE EC=1.7.5.1 {ECO:0000256|ARBA:ARBA00012500};
GN ORFNames=ACM01_02790 {ECO:0000313|EMBL:KMS76788.1};
OS Streptomyces viridochromogenes.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1938 {ECO:0000313|EMBL:KMS76788.1, ECO:0000313|Proteomes:UP000037432};
RN [1] {ECO:0000313|EMBL:KMS76788.1, ECO:0000313|Proteomes:UP000037432}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 3414 {ECO:0000313|EMBL:KMS76788.1,
RC ECO:0000313|Proteomes:UP000037432};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a quinol + nitrate = a quinone + H2O + nitrite;
CC Xref=Rhea:RHEA:56144, ChEBI:CHEBI:15377, ChEBI:CHEBI:16301,
CC ChEBI:CHEBI:17632, ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.7.5.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001854};
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004202};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMS76788.1}.
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DR EMBL; LFNT01000002; KMS76788.1; -; Genomic_DNA.
DR RefSeq; WP_048579387.1; NZ_LFNT01000002.1.
DR AlphaFoldDB; A0A0J7ZNS5; -.
DR PATRIC; fig|1938.3.peg.159; -.
DR OrthoDB; 9759518at2; -.
DR Proteomes; UP000037432; Unassembled WGS sequence.
DR GO; GO:0009325; C:nitrate reductase complex; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0008940; F:nitrate reductase activity; IEA:InterPro.
DR GO; GO:0042126; P:nitrate metabolic process; IEA:InterPro.
DR CDD; cd02776; MopB_CT_Nitrate-R-NarG-like; 1.
DR CDD; cd02750; MopB_Nitrate-R-NarG-like; 1.
DR Gene3D; 3.40.50.12440; -; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR037943; MopB_CT_Nitrate-R-NarG-like.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR006655; Mopterin_OxRdtase_prok_CS.
DR InterPro; IPR027467; MopterinOxRdtase_cofactor_BS.
DR InterPro; IPR006468; NarG.
DR NCBIfam; TIGR01580; narG; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR PANTHER; PTHR43105:SF2; RESPIRATORY NITRATE REDUCTASE 2 ALPHA CHAIN; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00551; MOLYBDOPTERIN_PROK_1; 1.
DR PROSITE; PS00490; MOLYBDOPTERIN_PROK_2; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Membrane {ECO:0000256|ARBA:ARBA00022475};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 60..124
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 1234 AA; 136891 MW; 04AAEE43DEAC438D CRC64;
MTDTRTPPTP PAEPPPEPGA ALLRAGRFFR PGTPAPDLHS VRLTGGREAD AFYRDRWSHD
KVVDSTHGVN CTGSCRWKVY VKDGIITWET QQTDYPSVGP DRPEYEPRGC PRGAAFSWYT
YSPTRVRYPY VRGVLLEMYR EAKQRLRDPV LAWADVQSDP ERRRRYQRAR GKGGLVRASW
DEAIEIVAAA HVHTIRTYGP DRIAGFSPIP AMSMVSHAAG ARFHSLIGAP MLSFYDWYAD
LPVASPQVFG DQTDVPESGD WWDAAYLMMW GSNVPVTRTP DAHWMAEARY RGQKVVVVAP
DYADNAKFAD EWLHPHPGTD GALALAMGHV ILKEFFVDRE TPFFADYVRQ FTDLPFLVTL
EERDGAYVPA KFLRASDLGQ RGASAEWKTV VLDAATGRAV APNGSLGFRW SESGEGRWNL
ELGDIRPQLS LYGSEVSAGV EVLLPRFDTE GGSHGQGRGD VVRRGVPATK LGGAHGPLVT
TVFDLLLAQY GVGRRGLPGR WPVSYDDADA PGTPAWQEAH TSVPAVRCIR IAREFARTAE
RSKGRCMILM GAGTNHWFHS ETIYRAFLAL LQLTGCQGRN GGGWAHYVGQ EKCRPVTGWA
TLAAASDWAR PPRQMIGTAY WFLNTDQWRY DRFTADVLAS PLGTGRFRGM TGADCLALSA
RVGWMPSYPT FDRNPLELGE TFGDPVSRVV AELRAGTLKF ACEDPDAPEN WPRVLTLWRA
NLLGSSAKGA EYFTRHLLGT HSSLQAEEAP QDVRPREVTW RDEAPEGKLD LLLSLDFRQT
SSTLLSDVVL PAATWYEKHD LSSTDMHPYV HSFTPAVDPP WQARTDFDTF KALAERLSEL
AVGHLGVRKD LVATPLQHDT PGEIAQPGGV VLDWRRGECD PVPGRTMPQL TVVERDYTAI
GARFTTLGPL AEQLGLPAKG ITLKPDEEVE DLRHLNGVTP DGRPSLDTAV KAANTILALS
GTTNGRLATQ GFRTLEARTG QEMAHLAAEH EGKRVTYADT QAAPVPVITS PEWSGSESGG
RRYTAFTLNT EHLKPWHTLT GRQHFFLDHD WIHELGEALP VYRPPLDMNQ LFGEPRLGPD
GQREVTVRYL TPHNKWSIHS EYQDNLFMLA LSRGGQNIWM SPQDAEAIGV VDNDWVEAVN
RNGVVVARAV VSHRMPAGTV YMHHAQERTV AVPKTETTGR RGGIHNSLTR LILKPSHLVG
GYAQLSWAFN YLGPTGNQRD EVTVVRRRSQ EVEY
//
