ID A0A0J8QM05_COCIT Unreviewed; 316 AA.
AC A0A0J8QM05;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Nucleoside-diphosphate-sugar epimerase {ECO:0000313|EMBL:KMU72238.1};
GN ORFNames=CISG_00547 {ECO:0000313|EMBL:KMU72238.1};
OS Coccidioides immitis RMSCC 3703.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=454286 {ECO:0000313|EMBL:KMU72238.1, ECO:0000313|Proteomes:UP000054559};
RN [1] {ECO:0000313|Proteomes:UP000054559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 3703 {ECO:0000313|Proteomes:UP000054559};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; DS268118; KMU72238.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J8QM05; -.
DR STRING; 454286.A0A0J8QM05; -.
DR Proteomes; UP000054559; Unassembled WGS sequence.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR CDD; cd05238; Gne_like_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43103:SF3; ADP-L-GLYCERO-D-MANNO-HEPTOSE-6-EPIMERASE; 1.
DR PANTHER; PTHR43103; NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Reference proteome {ECO:0000313|Proteomes:UP000054559}.
FT DOMAIN 3..204
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 316 AA; 34602 MW; 439DC89B08FCF307 CRC64;
MSILITGAAG FIGQELTTAL LKSTPSSTRL TITDVTTPII PVSAQEHASQ VKSVKADLTS
RSAVDGLISK SAAYDVVYLV HGIMSSASEA DFDLGMSVNF FATHYILDRL RHTMPGVKVV
FTSTLAVHGP TAAGFIINER NLPQIPTSSY VELLINDYSR RGFIDGRSVR LPTVTVRAGK
PTQAASSFAS GIIREPLNGK RSILPVKRDT ELWICSPYTV VENLILAKDI PKEAFGDSRS
VNLPGVKVTV QEMLDVLEEV AGKERRELVE EKYDPAIDRI VSGWSPNFDT SWAKSLGFKE
DMPFIHSVKR YIRDTS
//
